EP 3049406 A1 20160803 - SUBSTITUTED PHENYLALANINE DERIVATIVES AND USE THEREOF TO TREAT THROMBOTIC/THROMBOEMBOLIC DISEASES
Title (en)
SUBSTITUTED PHENYLALANINE DERIVATIVES AND USE THEREOF TO TREAT THROMBOTIC/THROMBOEMBOLIC DISEASES
Title (de)
SUBSTITUIERTE PHENYLALANIN-DERIVATE UND IHRE VERWENDUNG ZUR BEHANDLUNG VON THROMBOTISCHEN / THROMBOEMBOLISCHEN ERKRANKUNGEN
Title (fr)
DÉRIVÉS DE PHÉNYLALANINE SUBSTITUÉS ET LEUR UTILISATION POUR LE TRAITEMENT DE MALADIES THROMBOTIQUES/THROMBOEMBOLIQUES
Publication
Application
Priority
- EP 13186057 A 20130926
- EP 2014070316 W 20140924
- EP 14771915 A 20140924
Abstract (en)
[origin: WO2015044170A1] The invention relates to substituted phenylalanine derivatives of formula (I), in which R1 stands for a group of formula (II) or formula (III), R2 stands for hydrogen, fluorine, chlorine, methyl, or methoxy, R3 stands for hydrogen, fluorine, chlorine, C1-C4 alkyl, methoxy, or trifluoromethyl, and R4 stands for amino, cyano, C1-C3 alkoxy, C1-C3 alkylamino, C1-C3 alkoxycarbonyl, C1-C3 alkylcarbonylamino, C1-C3 alkysulfonyl, -S(O)2NR10R11, or 5- to 7-membered heterocyclyl bonded by means of a nitrogen atom. The invention further relates to the use thereof to produce drugs for treating and/or preventing illnesses, in particular cardiovascular diseases and/or perioperative heavy blood loss.
IPC 8 full level
C07D 403/12 (2006.01); A61K 31/41 (2006.01); A61K 31/416 (2006.01); A61K 31/4184 (2006.01); A61K 31/4196 (2006.01); A61K 31/4245 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); C07D 231/56 (2006.01); C07D 235/26 (2006.01); C07D 249/10 (2006.01); C07D 257/04 (2006.01); C07D 271/07 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01)
CPC (source: EP US)
C07D 231/56 (2013.01 - EP US); C07D 235/26 (2013.01 - EP US); C07D 237/32 (2013.01 - EP US); C07D 249/08 (2013.01 - EP US); C07D 249/10 (2013.01 - EP US); C07D 257/04 (2013.01 - EP US); C07D 271/07 (2013.01 - EP US); C07D 401/12 (2013.01 - EP US); C07D 403/12 (2013.01 - EP US); C07D 413/12 (2013.01 - EP US); C07B 2200/07 (2013.01 - US)
Citation (search report)
See references of WO 2015044170A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2015044170 A1 20150402; EP 3049406 A1 20160803; US 2016237044 A1 20160818
DOCDB simple family (application)
EP 2014070316 W 20140924; EP 14771915 A 20140924; US 201415024355 A 20140924