EP 3058956 A1 20160824 - Combined vaccination/radioterapy for cancer treatment
Title (en)
Combined vaccination/radioterapy for cancer treatment
Title (de)
Kombinierte Impfungs-/Strahlentherapie zur Krebsbehandlung
Title (fr)
Vaccination/radiothérapie combinée pour le traitement du cancer
Publication
Application
Priority
EP 15000507 A 20150223
Abstract (en)
The present invention concerns a a composition for use in the prevention or treatment of a subject suffering from a cancer in combination with radiotherapy, wherein said composition comprises a conjugate, eventually associated with pharmaceutically acceptable carrier, said conjugate comprising i) the Shiga Toxin B subunit (STxB), a fragment or a derivative thereof; and ii) at least one epitope associated with said cancer.
IPC 8 full level
A61K 41/00 (2006.01); A61K 47/48 (2006.01); A61N 5/10 (2006.01)
CPC (source: EP US)
A61K 38/164 (2013.01 - EP US); A61K 41/0038 (2013.01 - EP US); A61K 47/6415 (2017.08 - EP US); A61K 47/646 (2017.08 - EP US); A61N 5/10 (2013.01 - EP US); A61K 38/00 (2013.01 - US); A61K 39/00 (2013.01 - EP US); A61N 2005/1098 (2013.01 - EP US)
Citation (applicant)
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- US 5073627 A 19911217 - CURTIS BENSON M [US], et al
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- US 5730969 A 19980324 - HORA MANINDER SINGH [US], et al
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Citation (search report)
- [Y] EP 2740491 A1 20140611 - INST CURIE [FR], et al
- [A] WO 2012177624 A2 20121227 - UNIV JOHNS HOPKINS [US], et al
- [YD] HAICHEUR N ET AL: "The B subunit of Shiga toxin fused to a tumor antigen elicits CTL and targets dendritic cells to allow MHC class I-restricted presentation of peptides derived from exogenous antigens", THE JOURNAL OF IMMUNOLOGY, THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 165, no. 6, 15 September 2000 (2000-09-15), pages 3301 - 3308, XP002228666, ISSN: 0022-1767
- [A] REBECCA G. POMERANTZ ET AL: "The role of epidermal growth factor receptor in head and neck squamous cell carcinoma", CURRENT ONCOLOGY REPORTS, vol. 5, no. 2, 1 April 2003 (2003-04-01), pages 140 - 146, XP055205530, ISSN: 1523-3790, DOI: 10.1007/s11912-003-0101-z
- [A] R. HASSAN: "Tumor-Directed Radiation and the Immunotoxin SS1P in the Treatment of Mesothelin-Expressing Tumor Xenografts", CLINICAL CANCER RESEARCH, vol. 12, no. 16, 15 August 2006 (2006-08-15), pages 4983 - 4988, XP055157621, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-06-0441
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 3058956 A1 20160824; EP 3261673 A1 20180103; EP 3261673 B1 20210106; EP 3261673 B8 20210317; ES 2857704 T3 20210929; US 2018036368 A1 20180208; US 2019201480 A1 20190704; WO 2016134838 A1 20160901
DOCDB simple family (application)
EP 15000507 A 20150223; EP 16706528 A 20160222; EP 2016000303 W 20160222; ES 16706528 T 20160222; US 201615552405 A 20160220; US 201916243654 A 20190109