EP 3060306 A1 20160831 - COMPOSITIONS AND METHODS FOR USING AND IDENTIFYING ANTIMICROBIAL AGENTS
Title (en)
COMPOSITIONS AND METHODS FOR USING AND IDENTIFYING ANTIMICROBIAL AGENTS
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR VERWENDUNG UND IDENTIFIKATION ANTIMIKROBIELLER MITTEL
Title (fr)
COMPOSITIONS ET PROCÉDÉS POUR UTILISER ET IDENTIFIER DES AGENTS ANTIMICROBIENS
Publication
Application
Priority
- US 201361894484 P 20131023
- US 2014061583 W 20141021
Abstract (en)
[origin: WO2015061322A1] As disclosed herein methods are provided to identify compounds with antimicrobial activity, and methods for treating subjects by administering the compounds. In particular, the invention provides methods for treating and/or preventing microbial diseases and infections. One aspect of the present invention is directed to the identification of bactericidal compounds that function like chemokines. In one embodiment compounds are identified that bind to the extracellular domains of Bacillus anthracis FtsX. Compounds that bind to FtsX are then screened for bactericidal activity. In one embodiment compounds are screened to identify compounds that bind to the peptide.
IPC 8 full level
A61P 31/04 (2006.01)
CPC (source: EP US)
A61K 38/195 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 31/04 (2017.12 - EP); C12Q 1/18 (2013.01 - EP US); Y02A 50/30 (2017.12 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2015061322 A1 20150430; EP 3060306 A1 20160831; EP 3060306 A4 20171025; US 2016271220 A1 20160922; US 9937234 B2 20180410
DOCDB simple family (application)
US 2014061583 W 20141021; EP 14855489 A 20141021; US 201415031517 A 20141021