EP 3065549 A1 20160914 - METHODS FOR INHIBITING TIE2 KINASE USEFUL IN THE TREATMENT OF CANCER
Title (en)
METHODS FOR INHIBITING TIE2 KINASE USEFUL IN THE TREATMENT OF CANCER
Title (de)
VERFAHREN ZUR HEMMUNG VON TIE2-KINASE ZUR BEHANDLUNG VON KREBS
Title (fr)
MÉTHODES D'INHIBITION DE LA KINASE TIE2 UTILES DANS LE TRAITEMENT DU CANCER
Publication
Application
Priority
US 2013069005 W 20131107
Abstract (en)
[origin: WO2015069266A1] The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1Hpyrazol- 5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
IPC 8 full level
A01N 43/56 (2006.01); A01N 47/28 (2006.01); C07D 231/00 (2006.01)
CPC (source: AU EP KR)
A61K 9/0019 (2013.01 - AU KR); A61K 9/0053 (2013.01 - AU); A61K 9/10 (2013.01 - AU KR); A61K 31/337 (2013.01 - AU EP KR); A61K 31/357 (2013.01 - AU EP KR); A61K 31/4709 (2013.01 - AU EP); A61K 31/4725 (2013.01 - KR); A61K 45/06 (2013.01 - EP KR); A61P 35/00 (2017.12 - AU EP); A61P 35/02 (2017.12 - EP); A61P 35/04 (2017.12 - AU EP); A61P 43/00 (2017.12 - EP); A61K 2300/00 (2013.01 - AU KR)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2015069266 A1 20150514; AU 2013404949 A1 20160526; AU 2013404949 B2 20181018; AU 2019200261 A1 20190131; AU 2021200113 A1 20210304; CA 2929715 A1 20150514; CN 105873440 A 20160817; CN 105873440 B 20180601; CN 108464981 A 20180831; CN 108464981 B 20220624; EP 3065549 A1 20160914; EP 3065549 A4 20170524; JP 2017500371 A 20170105; JP 6568093 B2 20190828; KR 20160070188 A 20160617; KR 20210063475 A 20210601
DOCDB simple family (application)
US 2013069005 W 20131107; AU 2013404949 A 20131107; AU 2019200261 A 20190115; AU 2021200113 A 20210110; CA 2929715 A 20131107; CN 201380081931 A 20131107; CN 201810436668 A 20131107; EP 13896951 A 20131107; JP 2016552405 A 20131107; KR 20167014649 A 20131107; KR 20217015635 A 20131107