EP 3077393 A1 20161012 - COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
Title (en)
COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
Title (de)
ALS ATR-KINASEINHIBITOREN NÜTZLICHE VERBINDUNGEN
Title (fr)
COMPOSÉS UTILES EN TANT QU'INHIBITEURS DE LA KINASE ATR
Publication
Application
Priority
US 2013073482 W 20131206
Abstract (en)
[origin: WO2015084384A1] The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention are represented by formula (I-A) and formula (I-B); or a pharmaceutically acceptable salt, wherein the variables are as defined herein.
IPC 8 full level
C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61P 35/00 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 471/04 (2013.01); C07D 487/04 (2013.01)
Citation (search report)
See references of WO 2015084384A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2015084384 A1 20150611; EP 3077393 A1 20161012; JP 2016540773 A 20161228
DOCDB simple family (application)
US 2013073482 W 20131206; EP 13811718 A 20131206; JP 2016536710 A 20131206