EP 3079662 A1 20161019 - NOVEL PROCESS FOR PRODUCING TRANSMUCOSAL PHARMACEUTICAL FORMULATIONS AND FORMULATIONS THUS OBTAINED
Title (en)
NOVEL PROCESS FOR PRODUCING TRANSMUCOSAL PHARMACEUTICAL FORMULATIONS AND FORMULATIONS THUS OBTAINED
Title (de)
NAUERTIGES VERFAHREN ZUR HERSTELLUNG TRANSMUKOSALER PHARMAZEUTISCHER FORMULIERUNGEN UND DADURCH ERHALTENE FORMULIERUNGEN
Title (fr)
NOUVEAU PROCÉDÉ DE FABRICATION DE FORMULATIONS PHARMACEUTIQUES TRANSMUQUEUSES ET FORMULATIONS AINSI OBTENUES
Publication
Application
Priority
- FR 1302904 A 20131211
- FR 2014000265 W 20141210
Abstract (en)
[origin: WO2015086918A1] The present invention relates to a novel process for producing transmucosal pharmaceutical formulations and to formulations thus obtained. The process relates to the preparation of grains comprising a thermolabile substance as active ingredient, and consists in dissolving said substance in a ternary mixture composed of two amphiphilic binders, the melting point of which is between 40 and 60°C, and of an aqueous solvent such as, in particular, water, an aqueous-alcoholic solution or a water-soluble solvent. The grains thus obtained comprise a thermolabile active substance, two amphiphilic binders and an inert carrier. Use in obtaining translingual tablets wherein the thermolabile active substance is adrenalin.
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 31/00 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP US)
A61K 9/0056 (2013.01 - EP US); A61K 9/006 (2013.01 - US); A61K 9/1617 (2013.01 - EP US); A61K 9/1623 (2013.01 - US); A61K 9/1641 (2013.01 - US); A61K 9/1682 (2013.01 - US); A61K 9/2013 (2013.01 - EP US); A61K 9/2095 (2013.01 - EP US); A61K 31/137 (2013.01 - EP US); A61K 39/36 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US)
Citation (search report)
See references of WO 2015086918A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
FR 3014317 A1 20150612; FR 3014317 B1 20160422; EP 3079662 A1 20161019; US 2016361251 A1 20161215; WO 2015086918 A1 20150618; WO 2015086918 A9 20170223
DOCDB simple family (application)
FR 1302904 A 20131211; EP 14824036 A 20141210; FR 2014000265 W 20141210; US 201415104028 A 20141210