EP 3085776 B1 20200624 - OMEGA-TRANSAMINASE MUTANTS WITH ACTIVITY IMPROVEMENTS TOWARD KETONES AND METHODS FOR PRODUCING OPTICALLY PURE AMINES
Title (en)
OMEGA-TRANSAMINASE MUTANTS WITH ACTIVITY IMPROVEMENTS TOWARD KETONES AND METHODS FOR PRODUCING OPTICALLY PURE AMINES
Title (de)
OMEGA-TRANSAMINASEMUTANTEN MIT AKTIVITÄTSVERBESSERUNGEN GEGENÜBER KETONEN UND VERFAHREN ZUR HERSTELLUNG OPTISCH REINER AMINE
Title (fr)
MUTANTS D'OMÉGA-TRANSAMINASE PRÉSENTANT DES AMÉLIORATIONS D'ACTIVITÉS ENVERS LES CÉTONES ET PROCÉDÉS DE PRODUCTION D'AMINES OPTIQUEMENT PURES
Publication
Application
Priority
KR 20150049656 A 20150408
Abstract (en)
[origin: EP3085776A1] Provided is an omega-transaminase mutant with improved activity using a point mutation in an active site of an omega-transaminase. Specifically, provided is a method for improving activity and extending a substrate spectrum of omega-transaminase by introducing a point mutation into a wild-type omega-transaminase rendered by substituting tryptophan at position 58 with the other amino acid
IPC 8 full level
C12N 9/10 (2006.01); C12P 13/04 (2006.01)
CPC (source: EP KR US)
C12N 9/1096 (2013.01 - EP KR US); C12N 15/09 (2013.01 - US); C12N 15/63 (2013.01 - KR); C12P 13/001 (2013.01 - EP KR US); C12Y 206/01 (2013.01 - KR); C12Y 206/01018 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3085776 A1 20161026; EP 3085776 B1 20200624; KR 101869432 B1 20180620; KR 20160120673 A 20161018; US 10308916 B2 20190604; US 2016298092 A1 20161013
DOCDB simple family (application)
EP 16164530 A 20160408; KR 20160042226 A 20160406; US 201615094625 A 20160408