EP 3094744 A1 20161123 - METHOD OF PREDICTING THE RESPONSIVENESS OF A CANCER DISEASE TO TREATMENT ON THE BASIS OF DNA METHYLATION
Title (en)
METHOD OF PREDICTING THE RESPONSIVENESS OF A CANCER DISEASE TO TREATMENT ON THE BASIS OF DNA METHYLATION
Title (de)
VERFAHREN ZUR VERHERSAGE DES BEHANDLUNGSERFOLGES EINER KREBSERKRANKUNG AUF BASIS VON DNA METHYLIERUNG
Title (fr)
METHODE DE PREDICTION DE LA SENSIBILITE A DES MEDICAMENTS POUR LE CANCER SUR LA BASE DE METHYLATION D'ADN.
Publication
Application
Priority
- EP 14151345 A 20140115
- EP 2015050648 W 20150115
- EP 15700459 A 20150115
Abstract (en)
[origin: WO2015107105A1] The present invention relates to a method of predicting/determining the responsiveness of a cancer disease to treatment with an inhibitor of CD95/CD95L signalling comprising the steps of i) determining the methylation level of a DNA sequence located upstream of and/or in a gene involved in CD95/CD95L signalling in a sample obtained from a patient; and ii) predicting/determining the responsiveness of the cancer disease according to said methylation level.
IPC 8 full level
C12Q 1/6886 (2018.01)
CPC (source: EP)
C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/154 (2013.01)
Citation (search report)
See references of WO 2015107105A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
EP 2015050648 W 20150115; EP 15700459 A 20150115