EP 3105346 A1 20161221 - PREDICTIVE MRNA BIOMARKERS FOR THE PREDICTION OF THE TREATMENT WITH METHOTREXATE (MTX)
Title (en)
PREDICTIVE MRNA BIOMARKERS FOR THE PREDICTION OF THE TREATMENT WITH METHOTREXATE (MTX)
Title (de)
PRÄDIKTIVE MRNA BIOMARKER ZUR VORHERSAGE DER BEHANDLUNG MIT METHOTREXAT (MTX)
Title (fr)
BIOMARQUEURS ARNM PRÉDICTIFS DU TRAITEMENT AU MÉTHOTREXATE (MTX)
Publication
Application
Priority
- DE 102014101905 A 20140214
- EP 2015053095 W 20150213
Abstract (en)
[origin: WO2015121417A1] The present invention relates to predictive mRNA biomarkers which are used in combination with HLA-DRB4 for predicting the treatment with MTX (methotrexate). The present invention further relates to a method for predicting the treatment with MTX (methotrexate), comprising the detection of the predictive mRNA biomarkers in combination with HLA-DRB4 in patient samples, wherein the patients are classified as responders or non-responders.
IPC 8 full level
C12Q 1/68 (2006.01)
CPC (source: EP US)
C12Q 1/6883 (2013.01 - EP US); C12Q 2600/106 (2013.01 - EP US); C12Q 2600/158 (2013.01 - EP US); C12Q 2600/178 (2013.01 - EP US)
Citation (search report)
See references of WO 2015121417A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2015121417 A1 20150820; EP 3105346 A1 20161221; US 2017058348 A1 20170302
DOCDB simple family (application)
EP 2015053095 W 20150213; EP 15705277 A 20150213; US 201515118711 A 20150213