Global Patent Index - EP 3119743 A2

EP 3119743 A2 20170125 - AN IMPROVED PROCESS FOR THE PREPARATION OF AGOMELATINE POLYMORPHIC FORM-1

Title (en)

AN IMPROVED PROCESS FOR THE PREPARATION OF AGOMELATINE POLYMORPHIC FORM-1

Title (de)

VERBESSERTES VERFAHREN ZUR HERSTELLUNG VON MOLYBDÄN-SUCCINIMIDKOMPLEXEN VON POLYMORPHER AGOMELATIN FORM-1

Title (fr)

PROCÉDÉ AMÉLIORÉ POUR LA PRÉPARATION DE LA FORME POLYMORPHE 1 DE L'AGOMÉLATINE

Publication

EP 3119743 A2 20170125 (EN)

Application

EP 14886181 A 20141229

Priority

  • IN 1492CH2014 A 20140320
  • IN 2014050008 W 20141229

Abstract (en)

[origin: WO2015140812A2] The invention provides a process for preparation of polymorphic form I of Agomelatine comprising dissolving Agomelatine in a water miscible organic solvent to obtain Agomelatine solution (solution A), preparing a solution of water miscible organic solvent and water (solution B) and cooling to below 0 ºC, adding solution A to solution B at below 0 ºC and precipitating Agomelatine polymorphic Form 1.

IPC 8 full level

C07C 233/18 (2006.01)

CPC (source: EP)

C07C 231/24 (2013.01); C07B 2200/13 (2013.01)

C-Set (source: EP)

C07C 231/24 + C07C 233/18

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2015140812 A2 20150924; WO 2015140812 A3 20160303; EP 3119743 A2 20170125; EP 3119743 A4 20171122

DOCDB simple family (application)

IN 2014050008 W 20141229; EP 14886181 A 20141229