EP 3124976 B1 20180912 - IMPROVED BACTERIAL ENDOTOXIN TEST FOR THE DETERMINATION OF ENDOTOXINS
Title (en)
IMPROVED BACTERIAL ENDOTOXIN TEST FOR THE DETERMINATION OF ENDOTOXINS
Title (de)
VERBESSERTER BAKTERIELLER ENDOTOXINTEST ZUR BESTIMMUNG VON ENDOTOXINEN
Title (fr)
TEST D'ENDOTOXINE BACTÉRIENNE AMÉLIORÉE POUR LA DÉTERMINATION D'ENDOTOXINES
Publication
Application
Priority
EP 15178683 A 20150728
Abstract (en)
[origin: EP3124976A1] Herein is reported a method for determining bacterial endotoxin at low concentrations in a sample of an antibody (that has been produced using bacterial cells) comprising the following steps in the following order: i) adding magnesium ions to the sample, ii) diluting the sample, iii) dialyzing the sample having a pH-value of 5.7-8.0 against an endotoxin-free aqueous solution, and iv) determining bacterial endotoxin in the sample using a bacterial endotoxin test, particularly the limulus amoebocyte lysate assay.
IPC 8 full level
G01N 33/579 (2006.01)
CPC (source: CN EP IL KR US)
G01N 1/38 (2013.01 - CN IL US); G01N 33/56911 (2013.01 - CN IL US); G01N 33/579 (2013.01 - CN EP IL KR US); G01N 33/6854 (2013.01 - IL KR); G01N 2333/195 (2013.01 - IL KR); G01N 2400/50 (2013.01 - IL KR); Y02A 50/30 (2018.01 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3124976 A1 20170201; EP 3124976 B1 20180912; AR 105497 A1 20171011; AU 2016298598 A1 20180118; AU 2016298598 B2 20211202; BR 112018001748 A2 20180918; BR 112018001748 A8 20230425; CA 2989960 A1 20170202; CA 2989960 C 20230926; CN 108027374 A 20180511; CN 108027374 B 20200707; CN 111638346 A 20200908; DK 3124976 T3 20181210; ES 2699526 T3 20190211; HR P20181954 T1 20190125; IL 256660 A 20180228; IL 256660 B 20200630; IL 274576 A 20200630; IL 274576 B 20210531; JP 2018529978 A 20181011; JP 2021051080 A 20210401; JP 6800226 B2 20201216; JP 7164790 B2 20221102; KR 102630300 B1 20240126; KR 20180030415 A 20180322; LT 3124976 T 20181227; MX 2018000679 A 20181129; PL 3124976 T3 20190228; PT 3124976 T 20181120; RS 58167 B1 20190329; SI 3124976 T1 20181231; TR 201816369 T4 20181121; US 10585097 B2 20200310; US 11360085 B2 20220614; US 2018188249 A1 20180705; US 2020240988 A1 20200730; WO 2017017135 A1 20170202; WO 2017017135 A8 20170330
DOCDB simple family (application)
EP 15178683 A 20150728; AR P160102278 A 20160727; AU 2016298598 A 20160727; BR 112018001748 A 20160727; CA 2989960 A 20160727; CN 201680044156 A 20160727; CN 202010521942 A 20160727; DK 15178683 T 20150728; EP 2016067896 W 20160727; ES 15178683 T 20150728; HR P20181954 T 20181121; IL 25666017 A 20171231; IL 27457620 A 20200511; JP 2018524545 A 20160727; JP 2020194005 A 20201124; KR 20187006090 A 20160727; LT 15178683 T 20150728; MX 2018000679 A 20160727; PL 15178683 T 20150728; PT 15178683 T 20150728; RS P20181468 A 20150728; SI 201530465 T 20150728; TR 201816369 T 20150728; US 201615739503 A 20160727; US 202016774461 A 20200128