EP 3140429 A4 20180404 - METHODS AND COMPOSITIONS FOR SCD, CRT, CRT-D, OR SCA THERAPY IDENTIFICATION AND/OR SELECTION
Title (en)
METHODS AND COMPOSITIONS FOR SCD, CRT, CRT-D, OR SCA THERAPY IDENTIFICATION AND/OR SELECTION
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR SCD-, CRT-, CRT-D- ODER SCA-THERAPIEIDENTIFIZIERUNG UND/ODER AUSWAHL
Title (fr)
PROCÉDÉS ET COMPOSITIONS POUR L'IDENTIFICATION ET/OU LA SÉLECTION D'UN TRAITEMENT DU SCA OU DU SCD PAR CRT OU CRT-D
Publication
Application
Priority
- US 201461988323 P 20140505
- US 201562104098 P 20150116
- US 2015028095 W 20150428
Abstract (en)
[origin: US2015315644A1] Compositions, polynucleotides, probes, kits, methods, computer systems, treatment methods and genetic markers useful for assessing the risk of Sudden Cardiac Death (SCD), Sudden Cardiac Arrest (SCA), Ventricular Arrhythmia (VA), or Heart Failure (HF) are provided herein. The compositions, polynucleotides, probes, kits, methods, computer systems, treatment methods and genetic markers of the invention can provide patients selection for those that can be treated with an ICD or CRT-D based on assessing the presence of one or more Single Nucleotide Polymorphisms (SNPs) associated with any one of Sudden Cardiac Death (SCD), Sudden Cardiac Arrest (SCA), Ventricular Arrhythmia (VA), or Heart Failure (HF), and can indicate treatment with certain drugs such as beta-blockers.
IPC 8 full level
C12Q 1/68 (2018.01); G06F 19/22 (2011.01)
CPC (source: EP US)
C12Q 1/6883 (2013.01 - EP US); C12Q 2600/118 (2013.01 - EP US); C12Q 2600/156 (2013.01 - EP US)
Citation (search report)
- [XI] US 2011143345 A1 20110616 - SOYKAN ORHAN [US], et al
- [A] WO 2004076690 A2 20040910 - UNIV DUISBURG ESSEN [DE], et al
- [A] WO 2012094651 A2 20120712 - TRUSTEES OF THE UNIVERSITY OF ILLIOIS BOARD OF [US], et al
- [XI] HEINRICH WIENEKE ET AL: "Polymorphisms associated with ventricular tachyarrhythmias: rationale, design, and endpoints of the ?diagnostic data influence on disease management and relation of genomics to ventricular tachyarrhythmias in implantable cardioverter/defibrillator patients (DISCOVERY)? study", EUROPACE, W.B. SAUNDERS, GB, vol. 12, no. 3, 1 March 2010 (2010-03-01), pages 424 - 429, XP002665310, ISSN: 1099-5129, [retrieved on 20100205], DOI: 10.1093/EUROPACE/EUP444
- See references of WO 2015171370A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 2015315644 A1 20151105; CN 106460062 A 20170222; EP 3140429 A1 20170315; EP 3140429 A4 20180404; EP 3140429 B1 20200219; US 11312994 B2 20220426; US 2019017120 A1 20190117; WO 2015171370 A1 20151112
DOCDB simple family (application)
US 201514698812 A 20150428; CN 201580030366 A 20150428; EP 15789936 A 20150428; US 2015028095 W 20150428; US 201816149560 A 20181002