Global Patent Index - EP 3141537 A1

EP 3141537 A1 20170315 - A LABELING PRECURSOR COMPOUND AND METHOD FOR PRODUCING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME

Title (en)

A LABELING PRECURSOR COMPOUND AND METHOD FOR PRODUCING RADIOACTIVE FLUORINE LABELED COMPOUND USING THE SAME

Title (de)

FLUORINMARKIERUNGSVORLÄUFER UND VERFAHREN ZUR HERSTELLUNG EINER MIT RADIOAKTIVEM FLUORIN MARKIERTEN VERBINDUNG MIT DIESER VORLÄUFER

Title (fr)

COMPOSÉ PRECURSEUR DE MARQUAGE RADIOACTIF PAR FLUORINE ET PROCÉDÉ DE PRODUCTION DE COMPOSÉ DE MARQUAGE RADIOACTIF PAR FLUORINE L'UTILISANT CE COMPOSÉ PRECURSEUR

Publication

EP 3141537 A1 20170315 (EN)

Application

EP 16186503 A 20160831

Priority

JP 2015176566 A 20150908

Abstract (en)

There is provided a labeling precursor compound represented by the following general formula (2): wherein R 1 represents an alkynyl group, an alkynyloxy group, an azide group, an azidoalkyl group, an arylazide group, a monocyclic or condensed polycyclic aryl group or a nitrogen-containing heterocycle; R 2 and R 3 each independently represent an alkyl group or a hydroxyalkyl group which hydroxy group may be protected with a protecting group, and n is an integer of 1 or 2; R 6 represents an alkyl group or -CONR 11 R 12 wherein R 11 and R 12 each independently represent an alkyl group or a monocyclic or condensed polycyclic aryl group; and R 4 , R 5 , R 7 and R 8 each independently represent a hydrogen atom, an alkyl group or an alkoxy group.

IPC 8 full level

A61K 51/04 (2006.01); C07B 59/00 (2006.01); C07D 405/06 (2006.01)

CPC (source: EP US)

A61K 51/0453 (2013.01 - US); C07B 59/00 (2013.01 - EP US); C07D 405/06 (2013.01 - EP US); C07B 2200/05 (2013.01 - US); Y02P 20/55 (2015.11 - EP US)

Citation (applicant)

Citation (search report)

  • [AD] EP 2759538 A1 20140730 - NIHON MEDIPHYSICS CO LTD [JP], et al
  • [X] CHUL-HEE CHO ET AL: "Nickel-Catalyzed Cross-Coupling of Neopentyl Arenesulfonates with Methyl and Primary Alkylmagnesium Bromides", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 70, no. 4, 1 February 2005 (2005-02-01), pages 1482 - 1485, XP055315110, ISSN: 0022-3263, DOI: 10.1021/jo048300c

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

EP 3141537 A1 20170315; EP 3141537 B1 20181107; AU 2016225781 A1 20170323; AU 2016225781 B2 20201022; CA 2940538 A1 20170308; ES 2704951 T3 20190320; JP 2017052713 A 20170316; JP 6523107 B2 20190529; US 10081620 B2 20180925; US 2017066748 A1 20170309

DOCDB simple family (application)

EP 16186503 A 20160831; AU 2016225781 A 20160905; CA 2940538 A 20160829; ES 16186503 T 20160831; JP 2015176566 A 20150908; US 201615254090 A 20160901