EP 3143162 A4 20170426 - MIRNA EXPRESSION SIGNATURE IN THE CLASSIFICATION OF THYROID TUMORS
Title (en)
MIRNA EXPRESSION SIGNATURE IN THE CLASSIFICATION OF THYROID TUMORS
Title (de)
MIRNA-EXPRESSIONSSIGNATUR IN DER KLASSIFIZIERUNG VON SCHILDDRÜSENTUMOREN
Title (fr)
SIGNATURE D'EXPRESSION D'ARNMI DANS LA CLASSIFICATION DES TUMEURS THYROÏDIENNES
Publication
Application
Priority
- US 201461992756 P 20140513
- US 201461992531 P 20140513
- US 201462069353 P 20141028
- US 201562139066 P 20150327
- US 2015030564 W 20150513
Abstract (en)
[origin: WO2015175660A1] The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.
IPC 8 full level
C12Q 1/68 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C12Q 1/6886 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01)
Citation (search report)
- [A] WO 2013063544 A1 20130502 - ASURAGEN INC [US]
- [A] ZI-MING YUAN ET AL: "Deregulation of microRNA expression in thyroid tumors", ZHEJIANG UNIVERSITY. JOURNAL. SCIENCE B: INTERNATIONAL BIOMEDICINE & BIOTECHNOLOGY JOURNAL, vol. 15, no. 3, 1 March 2014 (2014-03-01), CN, pages 212 - 224, XP055355031, ISSN: 1673-1581, DOI: 10.1631/jzus.B1300192
- [A] NIKIFOROVA MARINA N ET AL: "MicroRNA expression profiling of thyroid tumors: Biological significance and diagnostic utility", JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, THE ENDOCRINE SOCIETY, US, vol. 93, no. 5, 1 May 2008 (2008-05-01), pages 1600 - 1608, XP002636292, ISSN: 0021-972X, [retrieved on 20080212], DOI: 10.1210/JC.2007-2696
- [A] PIERLORENZO PALLANTE ET AL: "Deregulation of microRNA expression in thyroid neoplasias", NATURE REVIEWS. ENDOCRINOLOGY, vol. 10, no. 2, 19 November 2013 (2013-11-19), US, pages 88 - 101, XP055355049, ISSN: 1759-5029, DOI: 10.1038/nrendo.2013.223
- [A] H. MAZEH: "MicroRNA as a Diagnostic Tool in Fine-Needle Aspiration Biopsy of Thyroid Nodules", THE ONCOLOGIST, vol. 17, no. 8, 15 June 2012 (2012-06-15), US, pages 1032 - 1038, XP055355012, ISSN: 1083-7159, DOI: 10.1634/theoncologist.2012-0013
- See references of WO 2015175660A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2015175660 A1 20151119; BR 112016026575 A2 20171212; CA 2945531 A1 20151119; CA 2945531 C 20180130; CN 106460053 A 20170222; EP 3143162 A1 20170322; EP 3143162 A4 20170426; IL 248639 A0 20170131; JP 2017521051 A 20170803; JP 6216470 B2 20171018
DOCDB simple family (application)
US 2015030564 W 20150513; BR 112016026575 A 20150513; CA 2945531 A 20150513; CN 201580024961 A 20150513; EP 15792258 A 20150513; IL 24863916 A 20161031; JP 2016567582 A 20150513