EP 3165522 A4 20170628 - CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND USE
Title (en)
CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND USE
Title (de)
UNGESÄTTIGTE CYCLOPROPYLCHINOLINVERBINDUNG ALS LEUKOTRIEN-REZEPTORANTAGONIST UND VERWENDUNG
Title (fr)
COMPOSÉ DE QUINOLÉINE CYCLOPROPYLIQUE INSATURÉE UTILISÉ EN TANT QU'ANTAGONISTE DU RÉCEPTEUR DES LEUCOTRIÈNES ET SON UTILISATION
Publication
Application
Priority
- CN 201510316361 A 20150610
- CN 2015089362 W 20150910
Abstract (en)
[origin: EP3165522A1] The present invention discloses a cyclopropyl unsaturated quinoline compound used as leukotriene receptor antagonist and applications thereof, wherein the structural formula of the compound is as follows: The present invention also discloses an application of the compound or its pharmaceutically acceptable salts, hydrates, solvates, or prodrugs in preparing a drug for treating and/or preventing and/or delaying and/or providing adjuvant therapy for asthma and/or allergic rhinitis and asthma syndromes. A drug composition includes the cyclopropyl unsaturated quinoline compound or the pharmaceutically acceptable salts, hydrates, solvates, or prodrugs thereof. The compound series of the present invention has favorable foreground in preparing the drugs for treating and/or preventing and/or delaying and/or providing adjuvant therapy for asthma and/or allergic rhinitis and asthma syndromes. The compound series of the present invention has favorable foreground in preparing the drugs for treating and/or preventing and/or delaying and/or providing adjuvant therapy for asthma and/or allergic rhinitis and asthma syndromes.
IPC 8 full level
C07D 215/18 (2006.01); A61K 31/47 (2006.01); A61P 11/06 (2006.01); A61P 37/08 (2006.01)
CPC (source: CN EP US)
A61K 31/47 (2013.01 - EP US); A61P 11/06 (2017.12 - EP US); C07D 215/18 (2013.01 - CN EP US)
Citation (search report)
- [X] WO 2006058545 A1 20060608 - MEDICHEM SA [ES], et al
- See references of WO 2016197467A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 3165522 A1 20170510; EP 3165522 A4 20170628; EP 3165522 B1 20190821; CN 105085391 A 20151125; CN 105085391 B 20170822; JP 2017521414 A 20170803; JP 6279773 B2 20180214; US 10315997 B2 20190611; US 10487058 B2 20191126; US 2018118687 A1 20180503; US 2019248746 A1 20190815; WO 2016197467 A1 20161215
DOCDB simple family (application)
EP 15894735 A 20150910; CN 2015089362 W 20150910; CN 201510316361 A 20150610; JP 2016576026 A 20150910; US 201515505040 A 20150910; US 201916391537 A 20190423