EP 3165523 B1 20200108 - COMPOSITION FOR INDUCING CELL REPROGRAMMING
Title (en)
COMPOSITION FOR INDUCING CELL REPROGRAMMING
Title (de)
ZUSAMMENSETZUNG ZUR AUSLÖSUNG VON ZELLPROGRAMMIERUNG
Title (fr)
COMPOSITIONS POUR INDUIRE LA REPROGRAMMATION CELLULAIRE
Publication
Application
Priority
- KR 20140081889 A 20140701
- KR 2015006718 W 20150630
Abstract (en)
[origin: EP3165523A2] The present invention relates to a composition for inducing cell reprogramming. The indazole derivative compound contained in the composition of the present invention shows an improved biological profile and at the same time can perform efficient cell reprogramming. In addition, unlike conventional compounds (e.g. riversine or BIO) for inducing low-molecular cell reprogramming, the indazole derivative compound of the present invention does not show cytotoxicity and thus is expected to have high growth in the market of cell therapy products when clinically applied. Conventional indazole derivative compounds have never known as a use for cell reprogramming. Compared with conventional indazole derivative compounds, the compound of the present invention has a great cell reprogramming ability while having no or little cytotoxicity.
IPC 8 full level
C07D 231/56 (2006.01); A61K 31/415 (2006.01); A61K 31/416 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61P 25/00 (2006.01); A61P 25/16 (2006.01); A61P 43/00 (2006.01); C07D 401/12 (2006.01)
CPC (source: EP KR US)
A61K 31/415 (2013.01 - EP US); A61K 31/416 (2013.01 - EP US); A61P 21/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 231/56 (2013.01 - EP KR US); C07D 401/06 (2013.01 - KR); C07D 401/12 (2013.01 - EP US); C07D 403/06 (2013.01 - KR); C07D 403/14 (2013.01 - KR); C12N 5/0654 (2013.01 - US); C12N 2506/1323 (2013.01 - US)
Citation (examination)
- WO 2004014922 A1 20040219 - ASTEX TECHNOLOGY LTD [GB], et al
- WO 2008089307 A2 20080724 - LEXICON PHARMACEUTICALS INC [US], et al
- WO 03064397 A1 20030807 - VERTEX PHARMA [US], et al
- WO 2013099041 A1 20130704 - FUJIFILM CORP [JP], et al
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3165523 A2 20170510; EP 3165523 A4 20170830; EP 3165523 B1 20200108; CN 106794172 A 20170531; CN 106794172 B 20200317; ES 2768803 T3 20200623; JP 2017526342 A 20170914; JP 6511075 B2 20190515; KR 101731624 B1 20170504; KR 20160003965 A 20160112; PL 3165523 T3 20200713; US 10858321 B2 20201208; US 2017158642 A1 20170608; WO 2016003169 A2 20160107; WO 2016003169 A3 20160616
DOCDB simple family (application)
EP 15815352 A 20150630; CN 201580036120 A 20150630; ES 15815352 T 20150630; JP 2016575756 A 20150630; KR 20140081889 A 20140701; KR 2015006718 W 20150630; PL 15815352 T 20150630; US 201515323342 A 20150630