Global Patent Index - EP 3177303 A4

EP 3177303 A4 20180117 - APOPTOTIC BODIES

Title (en)

APOPTOTIC BODIES

Title (de)

APOPTOTISCHE KÖRPER

Title (fr)

CORPS APOPTOTIQUES

Publication

EP 3177303 A4 20180117 (EN)

Application

EP 15830332 A 20150807

Priority

  • US 201462035246 P 20140808
  • US 2015044308 W 20150807

Abstract (en)

[origin: WO2016022972A1] This disclosure relates to apoptotic bodies. The disclosure particularly relates to a composition comprising the apoptotic bodies. The disclosure further relates to preparation of apoptotic bodies from stem cells. The disclosure also relates to medical treatments comprising the use of the composition comprising the apoptotic bodies. The apoptotic bodies may comprise apoptotic stem cells. The apoptosis of a cell may be induced by a starvation method, an ultra-violet irradiation method, a thermal stress method, a staurosporine method, or a combination thereof.

IPC 8 full level

A61K 35/12 (2015.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01); C12N 5/0775 (2010.01); C12N 5/0789 (2010.01)

CPC (source: EP US)

A61K 9/0053 (2013.01 - US); A61K 35/12 (2013.01 - EP US); A61K 35/28 (2013.01 - US); C12N 5/0663 (2013.01 - EP US)

Citation (search report)

  • [XI] PEI-HSUN SUNG ET AL: "Apoptotic adipose-derived mesenchymal stem cell therapy protects against lung and kidney injury in sepsis syndrome caused by cecal ligation puncture in rats", STEM CELL RESEARCH & THERAPY, BIOMED CENTRAL LTD, LONDON, UK, vol. 4, no. 6, 25 December 2013 (2013-12-25), pages 155, XP021175294, ISSN: 1757-6512, DOI: 10.1186/SCRT385
  • [XI] CHIA-LO CHANG ET AL: "Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in Rat sepsis syndrome induced by cecal puncture and ligation", JOURNAL OF TRANSLATIONAL MEDICINE, BIOMED CENTRAL, vol. 10, no. 1, 7 December 2012 (2012-12-07), pages 244, XP021134208, ISSN: 1479-5876, DOI: 10.1186/1479-5876-10-244
  • [XA] THUM THOMAS ET AL: "The Dying Stem Cell Hypothesis Immune Modulation as a Novel Mechanism for Progenitor Cell Therapy in Cardiac Muscle", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 46, no. 10, 2005, pages 1799 - 1802, XP029656539, ISSN: 0735-1097, DOI: 10.1016/J.JACC.2005.07.053
  • [XA] SAAS PHILIPPE ET AL: "Prospects of apoptotic cell-based therapies for transplantation and inflammatory diseases", IMMUNOTHERAPY, vol. 5, no. 10, October 2013 (2013-10-01), pages 1055 - 1073, XP009501748
  • See references of WO 2016022972A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2016022972 A1 20160211; CN 106659740 A 20170510; CN 106659740 B 20200623; EP 3177303 A1 20170614; EP 3177303 A4 20180117; EP 3177303 B1 20200729; US 10646518 B2 20200512; US 2017216364 A1 20170803

DOCDB simple family (application)

US 2015044308 W 20150807; CN 201580039370 A 20150807; EP 15830332 A 20150807; US 201515500726 A 20150807