Global Patent Index - EP 3181151 A1

EP 3181151 A1 20170621 - DETECTION OF HYDROGEN PEROXIDE

Title (en)

DETECTION OF HYDROGEN PEROXIDE

Title (de)

NACHWEIS VON WASSERSTOFFPEROXID

Title (fr)

DÉTECTION DE PÉROXYDE D'HYDROGÈNE

Publication

EP 3181151 A1 20170621 (EN)

Application

EP 17155379 A 20120816

Priority

  • US 201161524066 P 20110816
  • EP 12753305 A 20120816
  • US 2012051109 W 20120816

Abstract (en)

The present invention provides compounds of formula (I), (II) or (III), wherein R 1 and R 11 are boronic acid or a borate ester, useful for detection of hydrogen peroxide and methods of using the same.

IPC 8 full level

A61K 49/00 (2006.01); C07F 5/02 (2006.01)

CPC (source: EP US)

C07D 235/00 (2013.01 - EP US); C07D 241/54 (2013.01 - EP US); C07D 277/64 (2013.01 - EP US); C07F 5/02 (2013.01 - EP US); C07F 5/04 (2013.01 - US); C12Q 1/66 (2013.01 - EP US); G01N 33/5038 (2013.01 - US); G01N 2500/10 (2013.01 - US)

Citation (applicant)

  • PAQUETTE, LEO A.: "Principles of Modern Heterocyclic Chemistry", 1968, W.A. BENJAMIN
  • "The Chemistry of Heterocyclic Compounds, A Series of Monographs", vol. 13, 14,, 1950, JOHN WILEY & SONS
  • J. AM. CHEM. SOC., vol. 82, 1960, pages 5566
  • R. LAROCK: "Comprehensive Organic Transformations", 1989, VCH PUBLISHERS
  • T.W. GREENE; P.G.M. WUTS: "Protective Groups in Organic Synthesis", 1991, JOHN WILEY AND SONS
  • L. FIESER; M. FIESER: "Fieser and Fieser's Reagents for Organic Synthesis", 1994, JOHN WILEY AND SONS
  • "Encyclopedia of Reagents for Organic Synthesis", 1995, JOHN WILEY AND SONS
  • SUN, JS, CELL MOL LIFE SCI, vol. 53, 1997, pages 967 - 76
  • MAKENA, P; CHUNG, KT., ENVIRON. MOL. MUTAGEN, vol. 48, 2007, pages 404 - 413

Citation (search report)

  • [IP] WO 2011133800 A1 20111027 - UNIV CALIFORNIA [US], et al
  • [A] VICTOR M GONZALEZ: "Synthesis, Luminescence, and Applications of Coelenterazine and its Analogs", 26 February 2007 (2007-02-26), pages 17, XP055359111, Retrieved from the Internet <URL:http://www.chemistry.illinois.edu/research/organic/seminar_extracts/2006_2007/03GonzalezFINALAbstract.pdf>
  • [A] SAITO R ET AL: "Synthesis of boradiazaindaceneimidazopyrazinone conjugate as lipophilic and yellow-chemiluminescent chemosensor for superoxide radical anion", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 66, no. 3, 16 January 2010 (2010-01-16), pages 583 - 590, XP027534272, ISSN: 0040-4020, [retrieved on 20091123]
  • [A] G. C. VAN DE BITTNER ET AL: "In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 107, no. 50, 14 December 2010 (2010-12-14), pages 21316 - 21321, XP055040545, ISSN: 0027-8424, DOI: 10.1073/pnas.1012864107

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

US 2013045497 A1 20130221; US 8785652 B2 20140722; EP 2744521 A1 20140625; EP 2744521 B1 20170405; EP 3181151 A1 20170621; EP 3181151 B1 20200318; JP 2014525411 A 20140929; JP 6088515 B2 20170301; US 2014329257 A1 20141106; US 8937183 B2 20150120; WO 2013025885 A1 20130221

DOCDB simple family (application)

US 201213587387 A 20120816; EP 12753305 A 20120816; EP 17155379 A 20120816; JP 2014526207 A 20120816; US 2012051109 W 20120816; US 201414336877 A 20140721