EP 3187588 A4 20180110 - USE OF ALPHAVIRUS IN PREPARATION OF ANTITUMOR DRUGS
Title (en)
USE OF ALPHAVIRUS IN PREPARATION OF ANTITUMOR DRUGS
Title (de)
VERWENDUNG VON ALPHAVIRUS BEI DER HERSTELLUNG VON ANTITUMORMITTELN
Title (fr)
UTILISATION D'UN ALPHAVIRUS DANS LA PRÉPARATION DE MÉDICAMENTS ANTITUMORAUX
Publication
Application
Priority
- CN 201410425510 A 20140826
- CN 2015087945 W 20150824
Abstract (en)
[origin: EP3187588A1] Disclosed is use of alphavirus in preparation of antitumor drugs. The alphavirus is M1 virus or Getah virus. In addition, the specific tumor types sensitive to the abovementioned alphavirus treatment are further determined, so as to provide a safe and effective solution for antitumor drug administering schemes.
IPC 8 full level
C12N 15/86 (2006.01); A61K 35/768 (2015.01)
CPC (source: CN EP IL KR RU US)
A61K 35/76 (2013.01 - CN IL); A61K 35/768 (2013.01 - CN EP IL US); A61K 45/06 (2013.01 - CN IL); A61K 48/00 (2013.01 - IL KR RU); A61P 1/00 (2018.01 - EP IL); A61P 1/16 (2018.01 - EP IL); A61P 1/18 (2018.01 - EP IL); A61P 11/00 (2018.01 - EP IL); A61P 11/02 (2018.01 - EP IL); A61P 11/04 (2018.01 - EP IL); A61P 13/08 (2018.01 - EP IL); A61P 13/10 (2018.01 - EP IL); A61P 15/00 (2018.01 - EP IL); A61P 17/00 (2018.01 - EP IL); A61P 25/00 (2018.01 - EP IL); A61P 35/00 (2018.01 - EP IL RU); A61P 43/00 (2018.01 - EP IL); C12N 7/00 (2013.01 - IL US); C12N 15/1138 (2013.01 - IL US); C12N 15/86 (2013.01 - IL KR); C12N 2310/14 (2013.01 - IL US); C12N 2320/31 (2013.01 - IL US); C12N 2770/36132 (2013.01 - EP IL US); C12N 2770/36133 (2013.01 - IL KR); C12N 2770/36141 (2013.01 - IL KR)
C-Set (source: CN)
Citation (search report)
- [XI] WO 2007050074 A1 20070503 - MATHIS JAMES MICHAEL [US], et al
- [XI] SALVETTI ANNA ET AL: "Viruses and the nucleolus: The fatal attraction", BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, vol. 1842, no. 6, 27 December 2013 (2013-12-27), pages 840 - 847, XP028599502, ISSN: 0925-4439, DOI: 10.1016/J.BBADIS.2013.12.010
- [XP] YUAN LIN ET AL: "Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 111, no. 42, 6 October 2014 (2014-10-06), pages E4504 - E4512, XP055199074, ISSN: 0027-8424, DOI: 10.1073/pnas.1408759111
- [A] JUN HU ET AL: "Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein", CELL CYCLE, vol. 8, no. 20, 1 January 2009 (2009-01-01), US, pages 3328 - 3339, XP055411626, ISSN: 1538-4101, DOI: 10.4161/cc.8.20.9832
- [A] QUETGLAS J I ET AL: "Alphavirus vectors for cancer therapy", VIRUS RESEARCH, AMSTERDAM, NL, vol. 153, no. 2, 1 November 2010 (2010-11-01), pages 179 - 196, XP027367775, ISSN: 0168-1702, [retrieved on 20100806]
- See also references of WO 2016029833A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3187588 A1 20170705; EP 3187588 A4 20180110; EP 3187588 B1 20201118; AU 2015309403 A1 20160818; AU 2015309403 B2 20170316; CA 2939535 A1 20160303; CA 2939535 C 20200721; CN 104814984 A 20150805; CN 104814984 B 20170915; CN 107349226 A 20171117; CN 107349226 B 20200825; CN 107456463 A 20171212; CN 107456463 B 20221014; HK 1212925 A1 20160624; IL 247082 A0 20160929; IL 247082 B1 20230701; IL 247082 B2 20231101; JP 2017526612 A 20170914; JP 2019048863 A 20190328; JP 6441372 B2 20181219; KR 102125602 B1 20200623; KR 20160105523 A 20160906; KR 20180119706 A 20181102; MX 2016010058 A 20170427; MY 188734 A 20211227; NZ 722768 A 20180928; NZ 746338 A 20191025; RU 2016131756 A 20180207; RU 2693938 C2 20190708; SG 11201606707R A 20160929; TW 201615202 A 20160501; TW I609690 B 20180101; US 10517909 B2 20191231; US 11235011 B2 20220201; US 2017304380 A1 20171026; US 2020085892 A1 20200319; WO 2016029833 A1 20160303
DOCDB simple family (application)
EP 15835808 A 20150824; AU 2015309403 A 20150824; CA 2939535 A 20150824; CN 201410425510 A 20140826; CN 2015087945 W 20150824; CN 201710516707 A 20140826; CN 201710666533 A 20140826; HK 16101034 A 20160129; IL 24708216 A 20160803; JP 2016550515 A 20150824; JP 2018218457 A 20181121; KR 20167021337 A 20150824; KR 20187030942 A 20150824; MX 2016010058 A 20150824; MY PI2016702817 A 20150824; NZ 72276815 A 20150824; NZ 74633815 A 20150824; RU 2016131756 A 20150824; SG 11201606707R A 20150824; TW 104127467 A 20150824; US 201515118375 A 20150824; US 201916680885 A 20191112