Title (en)

DERIVATIVES OF MACROCYCLIC N-ARYL-TRICYCLOPYRIMIDINE-2-AMINE POLYETHERS AS INHIBITORS OF FTL3 AND JAK

Title (de)

DERIVATE VON MAKROCYCLISCHEN N-ARYL-TRICYCLOPYRIMIDIN-2-AMIN-POLYETHERN ALS INHIBITOREN VON FTL3 UND JAK

Title (fr)

DERIVES DE N-ARYL-TRICYCLOPYRIMIDINE-2-AMINE POLYETHERS MACROCYCLIQUES COMME INHIBITEURS DE LA FTL3 ET JAK

Publication

EP 3189061 A1 20170712 (FR)

Application

EP 15757491 A 20150902

Priority

• FR 1458204 A 20140902
• EP 2015070072 W 20150902

Abstract (en)

[origin: WO2016034637A1] The present invention relates to a compound with the following formula (I): (I) or a salt and/or a pharmaceutically acceptable solvate thereof, in particular for use as a drug, in particular in the treatment of cancer, as well as to the pharmaceutical compositions that contain same and to the methods for preparing same.

IPC 8 full level

C07D 498/08 (2006.01); A61K 31/527 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01)

CPC (source: EP US)

A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 498/08 (2013.01 - EP US); C07D 519/00 (2013.01 - EP US)

Citation (search report)

See references of WO 2016034637A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

FR 3025200 A1 20160304; FR 3025200 B1 20160923; BR 112017003880 A2 20171205; CN 106715445 A 20170524; CN 106715445 B 20190531; EP 3189061 A1 20170712; JP 2017525733 A 20170907; MX 2017002747 A 20171020; RU 2017108937 A 20181004; RU 2017108937 A3 20190225; US 10323043 B2 20190618; US 2017283432 A1 20171005; WO 2016034637 A1 20160310

DOCDB simple family (application)

FR 1458204 A 20140902; BR 112017003880 A 20150902; CN 201580053646 A 20150902; EP 15757491 A 20150902; EP 2015070072 W 20150902; JP 2017511996 A 20150902; MX 2017002747 A 20150902; RU 2017108937 A 20150902; US 201515508014 A 20150902