EP 3191448 A1 20170719 - METHOD FOR PRODUCING ASTAXANTHIN ESTERS
Title (en)
METHOD FOR PRODUCING ASTAXANTHIN ESTERS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON ASTAXANTHINESTERN
Title (fr)
PROCÉDÉ DE PRÉPARATION D'ESTERS ASTAXANTHINE
Publication
Application
Priority
- EP 14184483 A 20140911
- EP 2015068445 W 20150811
Abstract (en)
[origin: WO2016037785A1] The invention relates to an environmentally friendly, resource-conserving, and economical method for producing astaxanthin esters of formula 1, wherein astaxanthin of formula 2 is doubly esterified with fatty acid chlorides of general formula 3. For this purpose, compounds 2 and 3 are reacted in an organic solvent in the presence of a nitrogen-containing base of general formula 4. The invention further relates to the non-therapeutic use of diester 1, wherein R stands for a residue that is selected from the group consisting of C13-C19 alkyl, C13-C19 alkenyl, C13-C19 alkdienyl, and C13-C19 alktrienyl, in the nourishment of humans or animals, and to diester 1 produced according to the method, for therapeutic use as a medication and as an ingredient for a medical preparation.
IPC 8 full level
C07C 403/24 (2006.01); A61K 31/23 (2006.01)
CPC (source: CN EP KR US)
A61K 31/23 (2013.01 - KR); C07C 403/24 (2013.01 - CN EP KR US); A23V 2002/00 (2013.01 - CN); C07C 2601/16 (2017.04 - EP US)
Citation (search report)
See references of WO 2016037785A1
Citation (examination)
- PATRICIA HUBBARD ET AL: "Mechanism of Amine-Catalyzed Ester Formation from an Acid Chloride and Alcohol", JOURNAL OF ORGANIC CHEMISTRY, vol. 63, no. 3, 1 February 1998 (1998-02-01), pages 677 - 683, XP055520848, ISSN: 0022-3263, DOI: 10.1021/jo9716643
- ZHIHUI LIU ET AL: "4-( N,N -Dimethylamino)pyridine Hydrochloride as a Recyclable Catalyst for Acylation of Inert Alcohols: Substrate Scope and Reaction Mechanism", ORGANIC LETTERS, vol. 16, no. 1, 16 December 2013 (2013-12-16), US, pages 236 - 239, XP055520837, ISSN: 1523-7060, DOI: 10.1021/ol4030875
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016037785 A1 20160317; AU 2015314580 A1 20170406; BR 112017004761 A2 20171205; CA 2958386 A1 20160317; CN 106687443 A 20170517; EP 3191448 A1 20170719; JP 2017526712 A 20170914; KR 20170052630 A 20170512; MX 2017003237 A 20170629; RU 2017112051 A 20181011; RU 2017112051 A3 20190306; US 2017305849 A1 20171026
DOCDB simple family (application)
EP 2015068445 W 20150811; AU 2015314580 A 20150811; BR 112017004761 A 20150811; CA 2958386 A 20150811; CN 201580048767 A 20150811; EP 15750406 A 20150811; JP 2017513547 A 20150811; KR 20177009259 A 20150811; MX 2017003237 A 20150811; RU 2017112051 A 20150811; US 201515509905 A 20150811