EP 3193910 A1 20170726 - MUTANTS OF LEECH DERIVED NEUTROPHIL ELASTASE INHIBITORS AND USES THEREOF
Title (en)
MUTANTS OF LEECH DERIVED NEUTROPHIL ELASTASE INHIBITORS AND USES THEREOF
Title (de)
MUTANTE VON BLUTEGELABGELEITETEN INHIBITOREN DER NEUTROPHILEN ELASTASE UND VERWENDUNGEN DAVON
Title (fr)
MUTANTS D'INHIBITEURS DE L'ÉLASTASE NEUTROPHILE DÉRIVÉS DE SANGSUE ET LEURS UTILISATIONS
Publication
Application
Priority
- EP 2014066844 W 20140805
- EP 2015052192 W 20150203
Abstract (en)
[origin: WO2016020070A1] The invention relates to a mutant of an antistasin type serine proteinase (NE) inhibitor wherein said mutant is mutated with respect to the wild-type sequence at the amino acid residue immediately following the sixth cysteine residue. Such an antistasin type serine proteinase (NE) inhibitor is preferably selected from fahsin, guamerin, piguamerin, hirustasin and bdellastasin and mutant homologs.
IPC 8 full level
A61K 38/17 (2006.01); A61K 38/58 (2006.01); A61P 11/00 (2006.01)
CPC (source: EP)
A61P 11/00 (2017.12); C07K 14/811 (2013.01); C07K 14/815 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 2016020070A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
EP 2015052192 W 20150203; EP 15703058 A 20150203