Global Patent Index - EP 3196316 B1

EP 3196316 B1 20230222 - METHOD AND DEVICE FOR COMPARATIVE ANALYSIS OF miRNA EXPRESSION LEVEL

Title (en)

METHOD AND DEVICE FOR COMPARATIVE ANALYSIS OF miRNA EXPRESSION LEVEL

Title (de)

VERFAHREN UND VORRICHTUNG ZUR VERGLEICHENDEN ANALYSE VON MIRNA-EXPRESSIONSNIVEAUS

Title (fr)

PROCÉDÉ ET DISPOSITIF POUR L'ANALYSE COMPARATIVE DU NIVEAU D'EXPRESSION DE miARN

Publication

EP 3196316 B1 20230222 (EN)

Application

EP 15841913 A 20150915

Priority

  • JP 2014187685 A 20140916
  • JP 2015076085 W 20150915

Abstract (en)

[origin: EP3196316A1] Disclosed is a method for comparative analysis of the expression levels of target miRNAs among a plurality of body fluid samples. In the method for comparative analysis of the present invention, the expression levels of the target miRNAs in each body fluid sample are corrected using the expression level(s) of a correcting endogenous miRNA(s) that is/are simultaneously measured with the expression levels of the target miRNAs in the sample. As the correcting endogenous miRNA(s), one or more miRNAs selected from specific 10 kinds of correcting endogenous miRNAs is/are used. By the present invention, comparative analysis of target miRNAs among body fluid samples can be carried out more accurately than by conventional techniques.

IPC 8 full level

C12Q 1/68 (2006.01); G16B 40/10 (2019.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12N 15/09 (2006.01); C12Q 1/6816 (2018.01); C12Q 1/6876 (2018.01); G01N 33/53 (2006.01); G01N 37/00 (2006.01); G16B 25/10 (2019.01)

CPC (source: EP KR US)

C12M 1/00 (2013.01 - EP US); C12M 1/34 (2013.01 - EP KR US); C12N 15/09 (2013.01 - EP KR US); C12Q 1/68 (2013.01 - EP US); C12Q 1/6816 (2013.01 - EP KR US); C12Q 1/6876 (2013.01 - KR US); G01N 33/53 (2013.01 - EP KR US); G01N 37/00 (2013.01 - EP KR US); G16B 25/00 (2019.02 - EP US); G16B 25/10 (2019.02 - EP KR US); G16B 40/00 (2019.02 - EP US); G16B 40/10 (2019.02 - EP US); G16B 40/20 (2019.02 - KR); C12Q 2600/158 (2013.01 - KR US); C12Q 2600/178 (2013.01 - KR US)

C-Set (source: EP US)

C12Q 1/6816 + C12Q 2525/207 + C12Q 2537/165 + C12Q 2545/101

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

EP 3196316 A1 20170726; EP 3196316 A4 20180328; EP 3196316 A9 20181024; EP 3196316 B1 20230222; BR 112017003608 A2 20180130; BR 112017003608 B1 20231107; CA 2957267 A1 20160324; CA 2957267 C 20230314; CN 107075578 A 20170818; CN 107075578 B 20210601; JP 6819848 B2 20210127; JP WO2016043170 A1 20170622; KR 102350747 B1 20220113; KR 20170052530 A 20170512; US 11348663 B2 20220531; US 2017262581 A1 20170914; WO 2016043170 A1 20160324

DOCDB simple family (application)

EP 15841913 A 20150915; BR 112017003608 A 20150915; CA 2957267 A 20150915; CN 201580049304 A 20150915; JP 2015076085 W 20150915; JP 2015545966 A 20150915; KR 20167036349 A 20150915; US 201515511877 A 20150915