EP 3204516 A4 20180228 - ANGIOPOIETIN-2 BIOMARKERS PREDICTIVE OF ANTI-IMMUNE CHECKPOINT RESPONSE
Title (en)
ANGIOPOIETIN-2 BIOMARKERS PREDICTIVE OF ANTI-IMMUNE CHECKPOINT RESPONSE
Title (de)
PRÄDIKTIVE ANGIOPOIETIN-2-BIOMARKER FÜR ANTI-IMMUN-CHECKPOINT-REAKTION
Title (fr)
BIOMARQUEURS À BASE D'ANGIOPOÏÉTINE -2 UTILISÉS POUR LA PRÉDICTION DE LA RÉPONSE DE POINT DE CONTRÔLE ANTI-IMMUNITAIRE
Publication
Application
Priority
- US 201462060230 P 20141006
- US 201562218277 P 20150914
- US 201562218624 P 20150915
- US 2015053933 W 20151005
Abstract (en)
[origin: WO2016057367A1] The present invention is based on the identification of novel biomarkers predictive of responsiveness to anti-immune checkpoint therapies.
IPC 8 full level
C12Q 1/68 (2018.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01)
CPC (source: EP US)
C07K 16/22 (2013.01 - EP US); C07K 16/2818 (2013.01 - EP US); C12Q 1/6886 (2013.01 - US); G01N 33/5011 (2013.01 - US); G01N 33/5743 (2013.01 - US); G01N 33/57484 (2013.01 - EP US); A61K 2039/505 (2013.01 - EP US); C12Q 2600/106 (2013.01 - US); C12Q 2600/136 (2013.01 - US); G01N 2500/10 (2013.01 - EP US); G01N 2800/52 (2013.01 - EP US)
Citation (search report)
- [XY] WO 2013148288 A1 20131003 - GENENTECH INC [US], et al
- [XY] WO 2013106765 A1 20130718 - GENENTECH INC [US], et al
- [XP] WO 2014185540 A1 20141120 - EISAI R&D MAN CO LTD [JP]
- [Y] S.-S. CHAE ET AL: "Angiopoietin-2 Interferes with Anti-VEGFR2-Induced Vessel Normalization and Survival Benefit in Mice Bearing Gliomas", CLINICAL CANCER RESEARCH, vol. 16, no. 14, 15 July 2010 (2010-07-15), US, pages 3618 - 3627, XP055441515, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-09-3073
- [A] DREW M. PARDOLL: "The blockade of immune checkpoints in cancer immunotherapy", NATURE REVIEWS. CANCER, vol. 12, no. 4, 1 April 2012 (2012-04-01), GB, pages 252 - 264, XP055415943, ISSN: 1474-175X, DOI: 10.1038/nrc3239
- See references of WO 2016057367A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2016057367 A1 20160414; WO 2016057367 A8 20170420; AU 2015328411 A1 20170504; AU 2015328411 B2 20211125; AU 2015328411 C1 20220303; CA 2963091 A1 20160414; EP 3204516 A1 20170816; EP 3204516 A4 20180228; EP 3204516 B1 20230426; US 2017248603 A1 20170831
DOCDB simple family (application)
US 2015053933 W 20151005; AU 2015328411 A 20151005; CA 2963091 A 20151005; EP 15848684 A 20151005; US 201515516774 A 20151005