Global Patent Index - EP 3211073 A4

EP 3211073 A4 20180321 - REPLICATIVE VACCINIA VIRUS VECTOR HIV VACCINE

Title (en)

REPLICATIVE VACCINIA VIRUS VECTOR HIV VACCINE

Title (de)

VEKTOR-HIV-IMPFSTOFF MIT REPLIKATIVEM VACCINIA-VIRUS

Title (fr)

VACCIN ANTI-VIH A VECTEUR DE VIRUS DE LA VACCINE REPLICATIF

Publication

EP 3211073 A4 20180321 (EN)

Application

EP 15852404 A 20151019

Priority

  • CN 201410558649 A 20141020
  • CN 2015092170 W 20151019

Abstract (en)

[origin: EP3211073A1] Provided is a recombinant replicative vaccinia virus, the virus comprising a polynucleotide encoding HSV-TK and HIV antigens. Also provided is a live vector HIV vaccine composition comprising the recombinant replicative vaccinia virus.

IPC 8 full level

C12N 7/01 (2006.01); A61K 39/12 (2006.01); A61K 39/21 (2006.01); A61P 31/18 (2006.01); C07K 14/005 (2006.01)

CPC (source: EP US)

A61K 39/12 (2013.01 - EP US); A61K 39/21 (2013.01 - EP US); A61K 39/39 (2013.01 - US); A61P 31/18 (2018.01 - EP); C07K 14/005 (2013.01 - EP US); C07K 14/16 (2013.01 - US); C12N 15/09 (2013.01 - US); C12N 15/867 (2013.01 - US); A61K 39/00 (2013.01 - EP US); A61K 48/00 (2013.01 - US); A61K 2039/5256 (2013.01 - EP US); A61K 2039/53 (2013.01 - US); C12N 7/00 (2013.01 - US); C12N 2710/24143 (2013.01 - EP US); C12N 2740/16134 (2013.01 - EP US)

Citation (search report)

  • [Y] WO 2004087047 A2 20041014 - UNIV ARIZONA [US], et al
  • [Y] EP 1992358 A1 20081119 - CHINESE CT FOR DISEASE CONTROL [CN]
  • [Y] DE 10056747 A1 20010531 - SHAO YIMING [CN], et al & DATABASE Geneseq [online] 11 September 2003 (2003-09-11), "HIV-1 subtype C DNA fragment.", retrieved from EBI accession no. GSN:AAH20870 Database accession no. AAH20870 & DATABASE Geneseq [online] 11 September 2003 (2003-09-11), "HIV-1 subtype (C/B') DNA fragment SEQ ID 3.", retrieved from EBI accession no. GSN:AAH20869 Database accession no. AAH20869
  • [A] METZGER C ET AL: "HUMAN CYTOMEGALOVIRUS UL97 KINASE CONFERS GANCICLOVIR SUSCEPTIBILITY TO RECOMBINANT VACCINIA VIRUS", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 68, no. 12, 1 December 1994 (1994-12-01), pages 8423 - 8427, XP009016053, ISSN: 0022-538X
  • [Y] VASSAUX G ET AL: "USE OF SUICIDE GENES FOR CANCER GENE THERAPY: STUDY OF THE DIFFERENT APPROACHES", EXPERT OPINION ON BIOLOGICAL THE, INFORMA HEALTHCARE, ASHLEY, LONDON; GB, vol. 4, no. 4, 1 January 2004 (2004-01-01), pages 519 - 530, XP009061810, ISSN: 1471-2598, DOI: 10.1517/14712598.4.4.519
  • [Y] SHAO Y ET AL: "P14-15 LB. The safety and immunogenicity of HIV-1 vaccines based on DNA and replication competent vaccinia vector in phase I clinical trial", RETROVIROLOGY, BIOMED CENTRAL LTD., LONDON, GB, vol. 6, no. Suppl 3, 22 October 2009 (2009-10-22), pages P404, XP021064133, ISSN: 1742-4690, DOI: 10.1186/1742-4690-6-S3-P404
  • [Y] G. DARBY ET AL: "Evidence that the 'Active Centre' of the Herpes Simplex Virus Thymidine Kinase Involves an Interaction between Three Distinct Regions of the Polypeptide", JOURNAL OF GENERAL VIROLOGY., vol. 67, no. 4, 1 April 1986 (1986-04-01), GB, pages 753 - 758, XP055449470, ISSN: 0022-1317, DOI: 10.1099/0022-1317-67-4-753 & DATABASE EMBL [online] 18 November 1986 (1986-11-18), "Herpes simplex virus type 1 (strain SC16) gene for thymidine kinase", retrieved from EBI accession no. EM_STD:X03764 Database accession no. X03764
  • [T] ZHANG QICHENG ET AL: "Improved safety of a replication-competent poxvirus-based HIV vaccine with the introduction of the HSV-TK/GCV suicide gene system", VACCINE, ELSEVIER, AMSTERDAM, NL, vol. 34, no. 30, 16 May 2016 (2016-05-16), pages 3447 - 3453, XP029605822, ISSN: 0264-410X, DOI: 10.1016/J.VACCINE.2016.05.012
  • [Y] PANTALEO GIUSEPPE ET AL: "Poxvirus vector-based HIV vaccines", CURRENT OPINION IN HIV AND, LIPPINCOTT WILLIAMS & WILKINS, US, vol. 5, no. 5, 1 September 2010 (2010-09-01), pages 391 - 396, XP009141668, ISSN: 1746-6318
  • See also references of WO 2016062226A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

EP 3211073 A1 20170830; EP 3211073 A4 20180321; CN 105586319 A 20160518; CN 105586319 B 20210108; US 2018119171 A1 20180503; WO 2016062226 A1 20160428

DOCDB simple family (application)

EP 15852404 A 20151019; CN 201410558649 A 20141020; CN 2015092170 W 20151019; US 201815520183 A 20180112