EP 3213082 A1 20170906 - VAV3 AS A MARKER FOR CANCER
Title (en)
VAV3 AS A MARKER FOR CANCER
Title (de)
VAV3 ALS KREBSMARKER
Title (fr)
VAV3 EN TANT QUE MARQUEUR DU CANCER
Publication
Application
Priority
- EP 14190513 A 20141027
- EP 2015074797 W 20151027
Abstract (en)
[origin: WO2016066604A1] The present invention provides the use of VAV3 protein, or of an isoform thereof, especially VAV3var2 protein, or of VAV3 mRNA, or of a transcript variant thereof, especially VAV3var2 mRNA, as a cancer marker, especially for ovarian cancer or endometrial cancer, as well as a use of an anti-VAV3var2 antibody. Further, a method relating to VAV3, for treatment decisions in regard to platinum-based chemotherapy, taxane-based chemotherapy and anti-angiogenic chemotherapy is provided as well as a method to screen for candidate therapeutic compounds, relating to VAV3var2.
IPC 8 full level
G01N 33/574 (2006.01)
CPC (source: EP)
C12Q 1/6886 (2013.01); G01N 33/57449 (2013.01); G01N 33/57484 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01); G01N 2500/04 (2013.01); G01N 2800/52 (2013.01); G01N 2800/56 (2013.01)
Citation (search report)
See references of WO 2016066604A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
EP 2015074797 W 20151027; EP 15785109 A 20151027