EP 3213760 A4 20180620 - SOLUBLE, STABLE, ANTI-INFLAMMATORY, PROLIFERATIVE, PROTECTIVE AND MUCOADHESIVE PHARMACEUTICAL COMPOSITIONS; USE THEREOF FOR TREATING MUCOSITIS CONDITIONS AND METHOD FOR PRODUCING SAME; BASE PHARMACEUTICAL COMPOSITION FOR PREPARING THE PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING SAME
Title (en)
SOLUBLE, STABLE, ANTI-INFLAMMATORY, PROLIFERATIVE, PROTECTIVE AND MUCOADHESIVE PHARMACEUTICAL COMPOSITIONS; USE THEREOF FOR TREATING MUCOSITIS CONDITIONS AND METHOD FOR PRODUCING SAME; BASE PHARMACEUTICAL COMPOSITION FOR PREPARING THE PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING SAME
Title (de)
LÖSLICHE, STABILE, ENTZÜNDUNGSHEMMENDE, PROLIFERATIVE, SCHÜTZENDE UND MUKOADHÄSIVE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN, VERWENDUNG DAVON ZUR BEHANDLUNG VON MUKOSITIS UND VERFAHREN ZUR HERSTELLUNG DAVON, PHARMAZEUTISCHE BASISZUSAMMENSETZUNG ZUR HERSTELLUNG DER PHARMAZEUTISCHEN ZUSAMMENSETZUNGEN UND VERFAHREN ZUR HERSTELLUNG DAVON
Title (fr)
COMPOSITIONS PHARMACEUTIQUES ANTI-INFLAMMATOIRES, PROLIFÉRATIVES, PROTECTRICES ET MUCOADHÉSIVES, SOLUBLES ET STABLES, LEUR UTILISATION DANS LE TRAITEMENT DES TABLEAUX DE MUCOSITE ET LEUR PROCÉDÉ D'OBTENTION, COMPOSITION PHARMACEUTIQUE DE BASE POUR LA PRÉPARATION DE CES COMPOSITIONS PHARMACEUTIQUES ET LEUR PROCÉDÉ D'OBTENTION
Publication
Application
Priority
BR 2014050002 W 20141027
Abstract (en)
[origin: EP3213760A1] The present invention relates to pharmaceutical compositions with mucoadhesive and sustained release characteristics containing the association of the extract or fractions of Curcuma longa L. with curcuminoid content greater than 5% and Bidens pilosa (Bd) extract, which has an important proliferative and anti-inflammatory effect, for the treatment of inflammatory diseases of the oral cavity (stomatitis) and of the gastrointestinal tract, as, for example, mucositis induced by radiotherapy and/or chemotherapy and aphthous lesions. Additionally, inflammatory skin lesions and vaginal mucositis. These are compositions obtained from a liquid base formulation containing an aqueous-based solvent system. The subject of the present invention is, therefore, to obtain pharmaceutical preparations, to develop their obtainment processes and to establish their uses. These preparations contain an association between the Bidens pilosa (or its fractions) extract and the Curcuma longa (or its fractions) extract at 1:10 to 10: 1 proportions, incorporated into semi-solid, liquid or solid pharmaceutical forms containing the synthetic or adhesive bio (mucus) component, diluents, carriers, binders, disintegrants, at the concentration ranges from 1 to 75% by weight, of the active agents of vegetable origin.
IPC 8 full level
A61K 36/9066 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 36/28 (2006.01); A61K 47/02 (2006.01); A61K 47/08 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61P 1/02 (2006.01); A61P 1/04 (2006.01)
CPC (source: EP US)
A61K 9/006 (2013.01 - EP US); A61K 9/20 (2013.01 - US); A61K 9/2018 (2013.01 - EP US); A61K 9/2031 (2013.01 - EP US); A61K 9/2054 (2013.01 - EP US); A61K 31/045 (2013.01 - US); A61K 36/28 (2013.01 - EP US); A61K 36/9066 (2013.01 - EP US); A61P 1/02 (2017.12 - EP); A61P 1/04 (2017.12 - EP); A61P 15/02 (2017.12 - EP); A61P 17/02 (2017.12 - EP); A61P 29/00 (2017.12 - EP)
Citation (search report)
- [A] WO 02064113 A1 20020822 - ACCESS PHARMA INC [US], et al
- See references of WO 2016065442A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3213760 A1 20170906; EP 3213760 A4 20180620; CA 2966060 A1 20160506; JP 2017533264 A 20171109; JP 7020915 B2 20220216; RU 2017114569 A 20181129; RU 2017114569 A3 20181129; US 11007244 B2 20210518; US 2017319642 A1 20171109; WO 2016065442 A1 20160506
DOCDB simple family (application)
EP 14905057 A 20141027; BR 2014050002 W 20141027; CA 2966060 A 20141027; JP 2017541143 A 20141027; RU 2017114569 A 20141027; US 201415522763 A 20141027