EP 3217961 A1 20170920 - METHOD FOR PREPARING NANOPRECIPITATES OF LOW MOLECULAR WEIGHT PEPTIDE OR PROTEIN
Title (en)
METHOD FOR PREPARING NANOPRECIPITATES OF LOW MOLECULAR WEIGHT PEPTIDE OR PROTEIN
Title (de)
VERFAHREN ZUR HERSTELLUNG VON NANOPRÄZIPITATEN VON NIEDERMOLEKULAREN PEPTIDEN ODER PROTEINEN
Title (fr)
PROCEDE DE PREPARATION DE NANOPRECIPITES DE PEPTIDE OU PROTEINE DE FAIBLE POIDS MOLECULAIRE
Publication
Application
Priority
- EP 14306318 A 20140826
- EP 2015069546 W 20150826
Abstract (en)
[origin: WO2016030418A1] The present invention relates to a method for the non-denaturing preparation of peptide or protein nanoprecipitates, or of peptide or protein and metal ion nanocoprecipitates, in which said protein or said peptide has a molecular weight no higher than 20 kDa, preferably no higher than 15 kDa, advantageously no higher than 10 kDa, and more advantageously no higher than 8 kDa. Said method includes a step of preparing a mixture of an aqueous solution of peptides or proteins, a nonsolvent of the peptide or protein, and optionally a water-soluble metal salt. The present invention also relates to a nanoprecipitate that can be obtained by the method according to the invention, as well as to a pharmaceutical composition comprising same, for use in the treatment or prevention of diabetes.
IPC 8 full level
CPC (source: CN EP US)
A61K 9/14 (2013.01 - CN EP US); A61K 9/1688 (2013.01 - CN EP US); A61K 38/26 (2013.01 - CN); A61K 38/27 (2013.01 - CN); A61K 38/28 (2013.01 - CN); C07K 1/32 (2013.01 - US); C07K 14/62 (2013.01 - US); A61K 38/00 (2013.01 - EP US)
Citation (search report)
See references of WO 2016030418A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 2990033 A1 20160302; CN 107205932 A 20170926; EP 3217961 A1 20170920; JP 2017530189 A 20171012; US 2018009841 A1 20180111; WO 2016030418 A1 20160303
DOCDB simple family (application)
EP 14306318 A 20140826; CN 201580058268 A 20150826; EP 15762940 A 20150826; EP 2015069546 W 20150826; JP 2017530423 A 20150826; US 201515506446 A 20150826