EP 3217999 A2 20170920 - METHODS FOR CHRONIC PAIN MANAGEMENT AND TREATMENT USING HCG
Title (en)
METHODS FOR CHRONIC PAIN MANAGEMENT AND TREATMENT USING HCG
Title (de)
VERFAHREN ZUR LINDERUNG UND BEHANDLUNG CHRONISCHER SCHMERZEN MIT HCG
Title (fr)
MÉTHODES DE GESTION DE LA DOULEUR CHRONIQUE À L'AIDE DE LA HCG
Publication
Application
Priority
- US 201414539940 A 20141112
- US 2015060348 W 20151112
Abstract (en)
[origin: WO2016077565A2] A gonadotropin is administered within a surprisingly effective narrow range for the purpose of treating chronic pain or other central sensitization sequelae. In one aspect, a recipient is provided with at least one of human chorionic gonadotropin (uHCG and /or rHCG), a pharmaceutically active HCG analogue, and a pharmaceutically active metabolite of the HCG or analogue at a dosage selected to provide an amount therapeutically bioequivalent to, a human subcutaneous dosage of between 120 IU/day and 170 IU/day of HCG, and more preferably between 140 IU/day and 160 IU/day of HCG. A combination product is also described, which includes a supply of the HCG-related drug, a delivery device, and a conversion scale for therapeutic bioequivalence that identifies the specific amount and route of administration for chronic pain or central sensitization as an indication of the drug.
IPC 8 full level
A61K 38/24 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP IL)
A61K 9/0019 (2013.01 - EP IL); A61K 9/08 (2013.01 - EP IL); A61K 9/19 (2013.01 - IL); A61K 38/24 (2013.01 - EP IL); A61M 5/20 (2013.01 - IL); A61M 5/284 (2013.01 - EP IL); A61M 5/31533 (2013.01 - EP IL); A61M 5/3155 (2013.01 - EP IL); A61P 25/04 (2017.12 - EP IL); A61P 43/00 (2017.12 - EP IL); A61K 9/19 (2013.01 - EP); A61M 5/20 (2013.01 - EP); A61M 2005/1405 (2013.01 - EP IL)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016077565 A2 20160519; WO 2016077565 A3 20160630; CN 107206057 A 20170926; EP 3217999 A2 20170920; EP 3217999 A4 20180620; HK 1244231 A1 20180803; IL 252239 A0 20170731; IL 252239 B 20220201
DOCDB simple family (application)
US 2015060348 W 20151112; CN 201580073070 A 20151112; EP 15859240 A 20151112; HK 18103822 A 20180319; IL 25223917 A 20170511