EP 3221450 A1 20170927 - AN IMPROVED PROCESS FOR THE PREPARATION OF PHARMACOPOEIAL GRADE INTERFERON ALPHA 2B
Title (en)
AN IMPROVED PROCESS FOR THE PREPARATION OF PHARMACOPOEIAL GRADE INTERFERON ALPHA 2B
Title (de)
VERBESSERTES VERFAHREN ZUR HERSTELLUNG VON INTERFERON ALPHA 2B IN ARZNEIBUCHQUALITÄT
Title (fr)
PROCÉDÉ AMÉLIORÉ POUR LA PRÉPARATION DE L'INTERFÉRON ALPHA 2B DE QUALITÉ CONFORME À LA PHARMACOPÉE
Publication
Application
Priority
- IN 3627MU2014 A 20141118
- IB 2015051009 W 20150211
Abstract (en)
[origin: WO2016079598A1] The present invention relates to a simple and scalable process for the production of pharmacopoeial grade Interferon alpha 2b by fed-batch fermentation followed by purification using chromatography techniques. The invention also relates to the recombinant expression of interferon alpha 2b in soluble form by fermentation to obtain high yields. The process involves clarification and chromatographic steps for the purification of Interferon alpha 2b.
IPC 8 full level
C07K 1/18 (2006.01); C07K 14/56 (2006.01); C12N 15/09 (2006.01)
CPC (source: EP)
C07K 14/56 (2013.01)
Citation (search report)
See references of WO 2016079598A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
IB 2015051009 W 20150211; EP 15823122 A 20150211