EP 3229020 B1 20200909 - IN-VITRO METHOD AND KIT FOR DIAGNOSING THE RISK OF SUFFERING FROM CARIES
Title (en)
IN-VITRO METHOD AND KIT FOR DIAGNOSING THE RISK OF SUFFERING FROM CARIES
Title (de)
IN-VITRO-VERFAHREN UND KIT ZUR DIAGNOSE DES RISIKOS VON KARIES
Title (fr)
MÉTHODE IN VITRO ET TROUSSE DE DIAGNOSTIC DE RISQUE DE PRÉSENTER DES CARIES
Publication
Application
Priority
- EP 14195383 A 20141128
- ES 2015070865 W 20151127
Abstract (en)
[origin: EP3026435A1] The present invention discloses a method for predicting caries risk in a subject and a kit based on said method, characterized in that said method comprises: (a) determining the concentration in saliva from said subject of at least one compound selected from each of salivary components (i) of the immune system, (ii) involved in microbial adhesion to a surface of the buccal cavity; and (iii) involved in metabolism in the buccal cavity or in regulating the pH thereof; (b) comparing a response variable calculated from more than one concentration determined in step (a) with a corresponding reference response variable in a population of subjects without caries or in a population of subjects with caries; and (c) determining caries risk based on the degree of difference in response variable compared in step (b), wherein a greater degree of difference between the response variable of the subject and the corresponding reference response variable in a population of subjects without caries or in a population of subjects with caries, is indicative of higher caries risk in said subject.
IPC 8 full level
G01N 33/68 (2006.01); G01N 33/84 (2006.01)
CPC (source: EP US)
G01N 33/68 (2013.01 - EP US); G01N 33/6893 (2013.01 - US); G01N 33/84 (2013.01 - EP US); G01N 2800/18 (2013.01 - EP US); G01N 2800/60 (2013.01 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3026435 A1 20160601; EP 3229020 A1 20171011; EP 3229020 A4 20180725; EP 3229020 B1 20200909; US 2018136228 A1 20180517; US 2020271671 A1 20200827; WO 2016083656 A1 20160602
DOCDB simple family (application)
EP 14195383 A 20141128; EP 15862543 A 20151127; ES 2015070865 W 20151127; US 201515529626 A 20151127; US 202016868802 A 20200507