EP 3234116 B1 20210908 - METHODS OF TREATING TISSUE CALCIFICATION
Title (en)
METHODS OF TREATING TISSUE CALCIFICATION
Title (de)
VERFAHREN ZUR BEHANDLUNG VON GEWEBEVERKALKUNG
Title (fr)
MÉTHODES DE TRAITEMENT D'UNE CALCIFICATION TISSULAIRE
Publication
Application
Priority
- US 201462094943 P 20141219
- US 201562249781 P 20151102
- US 2015066646 W 20151218
Abstract (en)
[origin: WO2016100803A2] The present invention provides a method of treating NPP1 deficiency or NPP1-associated disease such as idiopathic infantile arterial calcification (IIAC), pseudoxanthoma elasticum, vascular calcification in chronic kidney disease (VCCKD), insulin resistance, hypophosphatemic rickets, myocardial ischemia, joint calcification, angioid streaks, and ossification of the posterior longitudinal ligament of the spine. The present invention provides a method for treating tissue calcification by administering soluble NPP1 to produce a transient increase in serum pyrophosphate levels.
IPC 8 full level
C12N 9/14 (2006.01); A61K 38/46 (2006.01); A61P 3/00 (2006.01); A61P 9/00 (2006.01); A61P 13/12 (2006.01); C12N 9/16 (2006.01)
CPC (source: EP KR RU US)
A61K 38/46 (2013.01 - EP KR RU US); A61P 3/00 (2018.01 - EP US); A61P 9/00 (2018.01 - EP US); A61P 13/12 (2018.01 - EP US); C12N 9/16 (2013.01 - EP KR RU US); C12Y 301/04001 (2013.01 - EP KR RU US); C12Y 306/01009 (2013.01 - EP RU US); C07K 2319/30 (2013.01 - EP KR US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2016100803 A2 20160623; WO 2016100803 A3 20160804; AU 2015364411 A1 20170608; BR 112017012928 A2 20180515; CA 2971414 A1 20160623; CN 107109381 A 20170829; CO 2017006032 A2 20171020; EP 3234116 A2 20171025; EP 3234116 A4 20180801; EP 3234116 B1 20210908; EP 3967755 A1 20220316; EP 3967755 B1 20240327; EP 4438118 A2 20241002; ES 2899895 T3 20220315; ES 2981606 T3 20241009; HK 1245662 A1 20180831; JP 2018500315 A 20180111; JP 2022003048 A 20220111; JP 2024010052 A 20240123; KR 20170095367 A 20170822; MX 2017007946 A 20170915; MX 2022011281 A 20221018; MX 2023006083 A 20230619; PL 3967755 T3 20240819; RU 2017119466 A 20190121; RU 2017119466 A3 20191220; RU 2770698 C2 20220421; US 10493135 B2 20191203; US 2018318400 A1 20181108; US RE49529 E 20230516
DOCDB simple family (application)
US 2015066646 W 20151218; AU 2015364411 A 20151218; BR 112017012928 A 20151218; CA 2971414 A 20151218; CN 201580069537 A 20151218; CO 2017006032 A 20170616; EP 15871159 A 20151218; EP 21192925 A 20151218; EP 24165223 A 20151218; ES 15871159 T 20151218; ES 21192925 T 20151218; HK 18105396 A 20180425; JP 2017531728 A 20151218; JP 2021148519 A 20210913; JP 2023181332 A 20231020; KR 20177019819 A 20151218; MX 2017007946 A 20151218; MX 2022011281 A 20170615; MX 2023006083 A 20170615; PL 21192925 T 20151218; RU 2017119466 A 20151218; US 201515536880 A 20151218; US 201517111156 A 20151218