EP 3237404 B1 20201111 - PROCESSES FOR PREPARING ASK1 INHIBITORS
Title (en)
PROCESSES FOR PREPARING ASK1 INHIBITORS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON ASK1-INHIBITOREN
Title (fr)
PROCÉDÉS DE PRÉPARATION D'INHIBITEURS DE L'ASK1
Publication
Application
Priority
- US 201462096391 P 20141223
- US 201562269064 P 20151217
- US 2015067511 W 20151222
Abstract (en)
[origin: WO2016106384A1] The present disclosure provides processes for the preparation of a compound of formula (A) which exhibits apoptosis signal-regulating kinase ("ASK1") inhibitory activity and is thus useful in the treatment of diseases such as kidney disease, diabetic nephropathy and kidney fibrosis. The disclosure also provides compounds that are synthetic intermediates.
IPC 8 full level
C07D 401/14 (2006.01); C07D 233/56 (2006.01)
CPC (source: CN EP KR US)
A61K 31/4439 (2013.01 - KR); A61P 1/16 (2018.01 - EP); A61P 3/00 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 9/00 (2018.01 - EP); A61P 9/12 (2018.01 - EP); A61P 11/00 (2018.01 - EP); A61P 13/12 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 37/06 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 233/56 (2013.01 - CN EP KR US); C07D 233/64 (2013.01 - EP KR US); C07D 401/14 (2013.01 - CN EP KR US); C07B 2200/13 (2013.01 - CN KR US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016106384 A1 20160630; AU 2015369668 A1 20170629; AU 2015369668 B2 20190418; BR 112017013382 A2 20180214; CA 2972192 A1 20160630; CA 2972192 C 20210706; CA 3100432 A1 20160630; CA 3100432 C 20230808; CA 3202893 A1 20160630; CN 107108519 A 20170829; CN 107108519 B 20201103; CN 112225699 A 20210115; CN 112225699 B 20231114; EA 201791070 A1 20171229; EP 3237404 A1 20171101; EP 3237404 B1 20201111; EP 3693366 A1 20200812; EP 3693366 B1 20230628; EP 3693366 B8 20230809; EP 3693366 C0 20230628; EP 4276095 A2 20231115; EP 4276095 A3 20240117; ES 2842749 T3 20210714; ES 2959007 T3 20240219; HK 1246275 A1 20180907; IL 252748 A0 20170831; JP 2018501265 A 20180118; JP 2019048859 A 20190328; JP 6439050 B2 20181219; KR 102040382 B1 20191104; KR 20170096186 A 20170823; MX 2017008417 A 20170928; PL 3237404 T3 20210504; PT 3237404 T 20210119; SG 11201704738U A 20170728; SI 3237404 T1 20210129; TW 201630901 A 20160901; TW 202019906 A 20200601; TW 202115016 A 20210416; TW I685491 B 20200221; TW I724770 B 20210411; TW I749934 B 20211211; US 10604490 B2 20200331; US 11261161 B2 20220301; US 2016244430 A1 20160825; US 2017233350 A1 20170817; US 2018022708 A1 20180125; US 2020283393 A1 20200910; US 2022135527 A1 20220505; US 9586933 B2 20170307; US 9771328 B2 20170926
DOCDB simple family (application)
US 2015067511 W 20151222; AU 2015369668 A 20151222; BR 112017013382 A 20151222; CA 2972192 A 20151222; CA 3100432 A 20151222; CA 3202893 A 20151222; CN 201580070610 A 20151222; CN 202011095355 A 20151222; EA 201791070 A 20151222; EP 15830935 A 20151222; EP 20167420 A 20151222; EP 23181912 A 20151222; ES 15830935 T 20151222; ES 20167420 T 20151222; HK 18105379 A 20180425; IL 25274817 A 20170607; JP 2017533552 A 20151222; JP 2018217384 A 20181120; KR 20177020153 A 20151222; MX 2017008417 A 20151222; PL 15830935 T 20151222; PT 15830935 T 20151222; SG 11201704738U A 20151222; SI 201531460 T 20151222; TW 104143271 A 20151222; TW 109102636 A 20151222; TW 109142683 A 20151222; US 201514757663 A 20151222; US 201715413154 A 20170123; US 201715680024 A 20170817; US 202016795329 A 20200219; US 202217579497 A 20220119