EP 3247790 A1 20171129 - CELL MATURATION PROCESS
Title (en)
CELL MATURATION PROCESS
Title (de)
ZELLREIFUNGSVERFAHREN
Title (fr)
PROCÉDÉ DE MATURATION DE CELLULES
Publication
Application
Priority
- GB 201501159 A 20150123
- GB 2016050146 W 20160122
Abstract (en)
[origin: WO2016116769A1] Disclosed are methods and procedures which may be applied to cells (including differentiating (or partially differentiated) cells, cells in the terminal stages of differentiation and/or differentiated cells) to facilitate late stage maturation towards mature erythrocyte lineages – in particular towards reticulocytes and/or enucleated (anucleate) mature erythrocytes. The disclosure provides a method in which mature enucleated erythrocytes and/or reticulocytes are produced maintaining and/or culturing stem cells (for example differentiating or differentiated stem cells) under one or more maturation conditions in which the pH, level of (dissolved) oxygen; and level of mechanical stress is controlled.
IPC 8 full level
C12N 5/078 (2010.01)
CPC (source: EP)
C12N 5/0641 (2013.01); C12N 2501/01 (2013.01); C12N 2501/125 (2013.01); C12N 2501/155 (2013.01); C12N 2501/415 (2013.01); C12N 2501/727 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01)
Citation (search report)
See references of WO 2016116769A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016116769 A1 20160728; EP 3247790 A1 20171129; GB 201501159 D0 20150311
DOCDB simple family (application)
GB 2016050146 W 20160122; EP 16702763 A 20160122; GB 201501159 A 20150123