Global Patent Index - EP 3250568 A1

EP 3250568 A1 20171206 - AN IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID

Title (en)

AN IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID

Title (de)

VERBESSERTES VERFAHREN ZUR HERSTELLUNG VON LINEZOLID

Title (fr)

PROCÉDÉ PERFECTIONNÉ POUR LA PRÉPARATION DE LINÉZOLIDE

Publication

EP 3250568 A1 20171206 (EN)

Application

EP 16876979 A 20160523

Priority

  • IN 201641013830 A 20160421
  • IB 2016053003 W 20160523

Abstract (en)

[origin: WO2017182853A1] The present invention relates to an improved process for the preparation of Linezolid. More specifically, the present invention relates to an improved process for preparing(S)-N-[[3-[3-fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl] phthalimide and (S)-glycidyl phthalimide intermediates, which are used in the preparation of Linezolid.

IPC 8 full level

C07D 413/00 (2006.01); C07D 263/00 (2006.01)

CPC (source: EP)

C07D 263/20 (2013.01); C07D 405/06 (2013.01); C07D 413/06 (2013.01)

Citation (third parties)

Third party : Symed Lab Limited / Michael Best

  • IN 201641013830 A 20160421
  • IN 5865CH2013 A 20150619 - OPTIMUS DRUGS P LTD [IN]
  • WO 9924393 A1 19990520 - UPJOHN CO [US], et al
  • WO 2014141067 A2 20140918 - BENOVA LABS PVT LTD [IN]
  • IN 1103CH2013 A 20130314
  • IN 281489 A
  • ANONYMOUS: "Sodium hydride", NEW JERSEY DEPARTMENT OF HEALTH AND SENIOR SERVICES HAZARDOUS SUBSTANCE FACT SHEET, March 1995 (1995-03-01), pages 1 - 6, XP055581846
  • ANONYMOUS: "Explosives Incident Report No. 170 - Static Ignition of Sodium Hydride", EXPLOSIVES ACCIDENT/ INCIDENT ABSTRACTS SEPT. 1961 THRU JUNE 1967, October 1967 (1967-10-01), pages 2pp, XP055679866
  • PANDEY BHAWANA, FULEKAR M.H.: "Environmental Management - Strategies for chemical disaster", RESEARCH JOURNAL OF CHEMICAL SCIENCES, vol. 1, no. 1, April 2011 (2011-04-01), pages 111 - 117, XP055581853
  • "Letters", CHEMICAL & ENGINEERING NEWS, 13 September 1982 (1982-09-13), pages 4, 5, 43, XP055581856
  • TREVOR LAIRD: "Special Feature Section: Safety of Chemical Processes- Safety Feature", ORGANIC PROCESS RESEARCH DEVELOPMENT, vol. 9, no. 6, 2005, pages 951, XP055581961
  • ANONYMOUS: "Letters", CHEMICAL & ENGINEERING NEWS, 13 June 1966 (1966-06-13), pages 6 - 9, XP055581966
  • See also references of WO 2017182853A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2017182853 A1 20171026; AU 2016403208 A1 20180510; AU 2016403208 B2 20181025; EP 3250568 A1 20171206; EP 3250568 A4 20180801; KR 101832115 B1 20180223; KR 20170128485 A 20171122; NZ 741891 A 20200529

DOCDB simple family (application)

IB 2016053003 W 20160523; AU 2016403208 A 20160523; EP 16876979 A 20160523; KR 20177029421 A 20160523; NZ 74189116 A 20160523