EP 3251680 B1 20230920 - VACCINE COMPOSITION CONTAINING SYNTHETIC ADJUVANT
Title (en)
VACCINE COMPOSITION CONTAINING SYNTHETIC ADJUVANT
Title (de)
IMPFSTOFFZUSAMMENSETZUNG MIT EINEM SYNTHETISCHEN ADJUVANS
Title (fr)
COMPOSITION DE VACCIN CONTENANT UN ADJUVANT SYNTHÉTIQUE
Publication
Application
Priority
- US 2009045033 W 20090522
- US 15466308 A 20080522
- US 13412708 A 20080605
- US 35171009 A 20090109
- EP 13172042 A 20090522
- EP 09751685 A 20090522
Abstract (en)
[origin: US2009181078A1] Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogeneous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier.
IPC 8 full level
A61K 31/7028 (2006.01); A61K 39/008 (2006.01); A61K 39/04 (2006.01); A61K 39/145 (2006.01); A61P 37/00 (2006.01)
CPC (source: EP US)
A61K 39/0005 (2013.01 - US); A61K 39/008 (2013.01 - EP US); A61K 39/04 (2013.01 - US); A61K 39/145 (2013.01 - US); A61K 39/39 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 11/08 (2017.12 - EP); A61P 31/22 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/04 (2017.12 - EP); A61P 39/06 (2017.12 - EP); C12N 7/00 (2013.01 - US); A61K 2039/53 (2013.01 - US); A61K 2039/55566 (2013.01 - US); A61K 2039/55572 (2013.01 - EP US); A61K 2039/57 (2013.01 - US); C12N 2760/16034 (2013.01 - US); C12N 2760/16071 (2013.01 - US); Y02A 50/30 (2017.12 - US)
Citation (examination)
"ADVERTISING: SYNTHETIC ADJUVANT", INTERNET CITATION, 15 May 2007 (2007-05-15), pages 1 - 6, XP002546530, ISSN: 0022-1767, Retrieved from the Internet <URL:http://www.jimmunol.org/cgi/issue_pdf/advertising_pdf/178/10.pdf> [retrieved on 20090917]
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
US 2009181078 A1 20090716; CN 102112135 A 20110629; CN 102112135 B 20140521; DK 2664332 T3 20170508; EP 2291190 A2 20110309; EP 2664332 A1 20131120; EP 2664332 B1 20170329; EP 3251680 A1 20171206; EP 3251680 B1 20230920; EP 3251680 C0 20230920; HK 1159485 A1 20120803; HR P20170585 T1 20170616; HU E031740 T2 20170728; US 11376325 B2 20220705; US 2011014274 A1 20110120; US 2011070290 A1 20110324; US 2012039994 A1 20120216; US 2014193459 A1 20140710; US 2016058860 A1 20160303; US 2018169226 A1 20180621; US 2020376116 A1 20201203; US 8343512 B2 20130101; WO 2009143457 A2 20091126; WO 2009143457 A3 20100429
DOCDB simple family (application)
US 35171009 A 20090109; CN 200980129010 A 20090522; DK 13172042 T 20090522; EP 09751685 A 20090522; EP 13172042 A 20090522; EP 17163093 A 20090522; HK 11113997 A 20111228; HR P20170585 T 20170412; HU E13172042 A 20090522; US 2009045033 W 20090522; US 201113277919 A 20111020; US 201313886666 A 20130503; US 201514849212 A 20150909; US 201815868460 A 20180111; US 202016899729 A 20200612; US 84339510 A 20100726; US 84339810 A 20100726