EP 3252070 A1 20171206 - PROCESS AND SYSTEM FOR OBTAINING BOTULINUM NEUROTOXIN

Title (en)

PROCESS AND SYSTEM FOR OBTAINING BOTULINUM NEUROTOXIN

Title (de)

VERFAHREN UND SYSTEM ZUR GEWINNUNG VON BOTULINUMNEUROTXIN

Title (fr)

PROCÉDÉ ET SYSTÈME PERMETTANT D'OBTENIR DE LA NEUROTOXINE BOTULIQUE

Publication

EP 3252070 A1 20171206 (EN)

Application

EP 17180720 A 20100712

Priority

US 50218109 A 20090713
EP 10733117 A 20100712
US 2010041745 W 20100712

Abstract (en)

Rapid, animal protein free, chromatographic process and system for obtaining high potency, high yield botulinum neurotoxin for research, therapeutic and cosmetic use.

IPC 8 full level

C07K 14/33 (2006.01); A61K 38/16 (2006.01); C12N 1/20 (2006.01); C12P 21/02 (2006.01)

CPC (source: CN EP KR US)

A61K 38/16 (2013.01 - KR); B01D 15/361 (2013.01 - EP US); B01D 15/362 (2013.01 - EP US); B01D 15/363 (2013.01 - EP US); C07K 1/00 (2013.01 - KR); C07K 1/18 (2013.01 - KR US); C07K 14/33 (2013.01 - CN EP KR US); C12N 1/20 (2013.01 - KR US); C12N 9/52 (2013.01 - EP US); C12P 21/02 (2013.01 - CN US); C12R 2001/145 (2021.05 - US); C12Y 304/24069 (2013.01 - EP US); Y02A 50/30 (2018.01 - EP)

Citation (applicant)

US 7445914 B2 20081104 - DONOVAN STEPHEN [US]
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US 7148041 B2 20061212 - DONOVAN STEPHEN [US]
US 7189541 B2 20070313 - DONOVAN STEPHEN [US]
US 60944906 A 20061212
US 9889608 A 20080407
US 93268907 A 20071031
US 93278907 A 20071031
US 23453708 A 20080919
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SCHANTZ E.J. ET AL.: "Properties and use of botulinum toxin and other microbial neurotoxins in medicine", MICROBIOL REV, vol. 56, no. 1, March 1992 (1992-03-01), pages 80 - 99
SCHANTZ E.J. ET AL.: "Neurological Disease and Therapy. Therapy with botulinum toxin", 1994, MARCEL DEKKER, article "Preparation and characterization of botulinum toxin type A for human treatment", pages: 41 - 49
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SIMPSON L.L. ET AL.: "Methods in Enzymology. Vol. 165, Microbial Toxins: Tools in Enzymology", vol. 165, 1988, ACADEMIC PRESS, article "Isolation and characterization of the botulinum neurotoxins", pages: 76 - 85
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GOODNOUGH, M. C., THESIS, 1994

Citation (search report)

[ID] US 2006228780 A1 20061012 - LUO MINGJIANG [US], et al
[I] WO 2006096164 A1 20060914 - ALLERGAN INC [US], et al
[I] GIMENEZ J. ET AL.: "SIMPLIFIED PURIFICATION METHOD FOR CLOSTRIDIUM BOTULINUM TYPE E TOXIN", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 53, no. 12, 1 January 1987 (1987-01-01), pages 2827 - 2830, XP002343950
[I] SIMPSON L L ET AL: "ISOLATION AND CHARACTERIZATION OF THE BOTULINUM NEUROTOXINS", METHODS IN ENZYMOLOGY, ACADEMIC PRESS, US, vol. 165, 1 January 1988 (1988-01-01), pages 76 - 85, XP002919764, ISSN: 0076-6879, DOI: 10.1016/S0076-6879(88)65015-4

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

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