EP 3271720 A4 20181107 - METABOLOMICS PROFILING OF CENTRAL NERVOUS SYSTEM INJURY
Title (en)
METABOLOMICS PROFILING OF CENTRAL NERVOUS SYSTEM INJURY
Title (de)
METABOLOMIKPROFILIERUNG DER VERLETZUNG DES ZENTRALEN NERVENSYSTEMS
Title (fr)
PROFIL MÉTABOLOMIQUE D'UNE LÉSION DU SYSTÈME NERVEUX CENTRAL
Publication
Application
Priority
- US 201562135886 P 20150320
- CA 2016050310 W 20160318
Abstract (en)
[origin: WO2016149808A1] A method of diagnosing central nervous system injuries such as acquired brain injury (ABI) and/or acquired spinal cord injury (ASI), including mild TBI (concussion or blast wave), mild ASI (contusion, stretch or partial cord transection), non-TBI brain injury and/or non-TSI spinal cord injury in a subject (animal or human). The method includes (a) obtaining a biological test sample from the subject, identifying metabolites in the subject's sample using metabolomics thereby obtaining a subject's metabolite matrix and generating a subject's profile using the patient's metabolite matrix; and (b) using multivariate statistical analysis and machine learning to compare the subject's profile with predetermined set of profiles of CNS injuries and a predetermined set of profiles of controls to determine if the subject has a CNS injury.
IPC 8 full level
G01N 33/48 (2006.01); A61B 5/00 (2006.01); G01N 24/08 (2006.01); G01N 33/483 (2006.01); G01N 33/487 (2006.01); G01N 33/68 (2006.01); G06F 15/18 (2006.01); G06F 19/00 (2018.01); G16B 40/20 (2019.01); G16B 40/30 (2019.01)
CPC (source: EP US)
G01N 33/483 (2013.01 - EP US); G01N 33/487 (2013.01 - EP US); G01N 33/6896 (2013.01 - EP US); G16B 40/00 (2019.01 - EP US); G16B 40/20 (2019.01 - EP); G16B 40/30 (2019.01 - EP); G16C 20/70 (2019.01 - EP US); G01N 24/08 (2013.01 - EP US); G01N 2570/00 (2013.01 - EP US); G01N 2800/28 (2013.01 - EP US); G01N 2800/2871 (2013.01 - EP US); G16B 40/10 (2019.01 - EP US); G16B 40/20 (2019.01 - US); G16B 40/30 (2019.01 - US)
Citation (search report)
- No further relevant documents disclosed
- See references of WO 2016149808A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2016149808 A1 20160929; CA 2980376 A1 20160929; CA 2980376 C 20211019; CN 108235734 A 20180629; CN 108235734 B 20191210; EP 3271720 A1 20180124; EP 3271720 A4 20181107; EP 3271720 B1 20211103; ES 2905320 T3 20220407; HR P20220055 T1 20220415; US 11519899 B2 20221206; US 2018074038 A1 20180315
DOCDB simple family (application)
CA 2016050310 W 20160318; CA 2980376 A 20160318; CN 201680029055 A 20160318; EP 16767575 A 20160318; ES 16767575 T 20160318; HR P20220055 T 20160318; US 201615560056 A 20160318