EP 3285807 A4 20181226 - CALICHEAMICIN CONSTRUCTS AND METHODS OF USE
Title (en)
CALICHEAMICIN CONSTRUCTS AND METHODS OF USE
Title (de)
CALICHEAMICINKONSTRUKT UND VERFAHREN ZUR VERWENDUNG
Title (fr)
CONSTRUCTIONS DE CALICHÉAMICINE D'ACIDE NUCLÉIQUE ET LEURS PROCÉDÉS D'UTILISATION
Publication
Application
Priority
- US 201562150693 P 20150421
- US 2016028530 W 20160421
Abstract (en)
[origin: WO2016172273A1] Provided herein are antibody drug conjugates (ADCs) comprising calicheamicin and methods of using the same to treat proliferative disorders.
IPC 8 full level
A61K 47/68 (2017.01); C07K 16/30 (2006.01)
CPC (source: EP KR US)
A61K 47/6809 (2017.07 - EP KR US); A61K 47/6851 (2017.07 - EP KR US); A61K 47/6889 (2017.07 - EP KR US); A61P 35/00 (2017.12 - EP); C07K 16/30 (2013.01 - EP KR US); A61K 2039/505 (2013.01 - EP KR US)
Citation (search report)
- [X] US 2003092198 A1 20030515 - MCBRIDE WILLIAM J [US], et al
- [X] US 5877296 A 19990302 - HAMANN PHILIP ROSS [US], et al
- [X] SENTER ET AL: "Potent antibody drug conjugates for cancer therapy", CURRENT OPINION IN CHEMICAL BIOLOGY, CURRENT BIOLOGY LTD, LONDON, GB, vol. 13, no. 3, 1 June 2009 (2009-06-01), pages 235 - 244, XP026285196, ISSN: 1367-5931, [retrieved on 20090504], DOI: 10.1016/J.CBPA.2009.03.023
- [XI] JOHN A. FLYGARE ET AL: "Antibody-Drug Conjugates for the Treatment of Cancer", CHEMICAL BIOLOGY & DRUG DESIGN, vol. 81, no. 1, 17 January 2013 (2013-01-17), pages 113 - 121, XP055121985, ISSN: 1747-0277, DOI: 10.1111/cbdd.12085
- [X] PHILIP R. HAMANN ET AL: "An Anti-MUC1 Antibody-Calicheamicin Conjugate for Treatment of Solid Tumors. Choice of Linker and Overcoming Drug Resistance", BIOCONJUGATE CHEMISTRY, vol. 16, no. 2, 1 March 2005 (2005-03-01), US, pages 346 - 353, XP055272665, ISSN: 1043-1802, DOI: 10.1021/bc049795f
- [X] A. D. RICART: "Antibody-Drug Conjugates of Calicheamicin Derivative: Gemtuzumab Ozogamicin and Inotuzumab Ozogamicin", CLINICAL CANCER RESEARCH, vol. 17, no. 20, 14 October 2011 (2011-10-14), US, pages 6417 - 6427, XP055524358, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-11-0486
- See references of WO 2016172273A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016172273 A1 20161027; AR 104333 A1 20170712; AU 2016250537 A1 20181108; BR 112017022682 A2 20180710; CA 2983158 A1 20161027; CL 2017002680 A1 20180427; CN 107849146 A 20180327; CO 2017010692 A2 20180131; EA 201792312 A1 20180629; EP 3285807 A1 20180228; EP 3285807 A4 20181226; HK 1246194 A1 20180907; IL 255161 A0 20171231; JP 2018515457 A 20180614; KR 20170139110 A 20171218; MA 41959 A 20180228; PE 20180599 A1 20180409; PH 12017501930 A1 20180319; SG 11201708629V A 20171129; TW 201713363 A 20170416; US 2018133337 A1 20180517
DOCDB simple family (application)
US 2016028530 W 20160421; AR P160101092 A 20160421; AU 2016250537 A 20160421; BR 112017022682 A 20160421; CA 2983158 A 20160421; CL 2017002680 A 20171020; CN 201680036382 A 20160421; CO 2017010692 A 20171019; EA 201792312 A 20160421; EP 16783812 A 20160421; HK 18105790 A 20180504; IL 25516117 A 20171020; JP 2017555554 A 20160421; KR 20177033533 A 20160421; MA 41959 A 20160421; PE 2017002310 A 20160421; PH 12017501930 A 20171020; SG 11201708629V A 20160421; TW 105112526 A 20160421; US 201615567904 A 20160421