EP 3286227 A2 20180228 - MULTISPECIFIC ANTIGEN-BINDING PROTEINS
Title (en)
MULTISPECIFIC ANTIGEN-BINDING PROTEINS
Title (de)
MULTISPEZIFISCHE ANTIGENBINDENDE PROTEINE
Title (fr)
PROTÉINES MULTISPÉCIFIQUES DE LIAISON À L'ANTIGÈNE
Publication
Application
Priority
- US 201562152735 P 20150424
- US 201562264291 P 20151207
- US 201662310555 P 20160318
- US 2016028850 W 20160422
Abstract (en)
[origin: WO2016172485A2] Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.
IPC 8 full level
C07K 16/46 (2006.01); A61K 39/00 (2006.01); G16B 20/30 (2019.01); G16B 20/50 (2019.01)
CPC (source: CN EP IL KR US)
A61K 39/3955 (2013.01 - IL); A61K 39/39558 (2013.01 - IL US); A61K 39/39566 (2013.01 - IL); A61K 39/44 (2013.01 - IL US); A61P 29/00 (2018.01 - CN EP IL); A61P 35/00 (2018.01 - CN EP IL); A61P 35/02 (2018.01 - EP IL); A61P 35/04 (2018.01 - EP IL); A61P 37/02 (2018.01 - CN EP IL); A61P 37/06 (2018.01 - EP IL); A61P 37/08 (2018.01 - CN EP IL); C07K 16/468 (2013.01 - CN EP IL KR US); G01N 33/6848 (2013.01 - IL); G16B 5/00 (2019.02 - IL); G16B 20/00 (2019.02 - IL); G16B 20/30 (2019.02 - EP KR US); G16B 20/50 (2019.02 - EP KR US); A61K 39/3955 (2013.01 - US); A61K 39/39566 (2013.01 - US); A61K 2039/505 (2013.01 - CN); A61K 2039/507 (2013.01 - IL US); C07K 2317/31 (2013.01 - CN EP IL KR US); C07K 2317/522 (2013.01 - CN EP IL KR US); C07K 2317/56 (2013.01 - CN EP IL KR US); G01N 33/6848 (2013.01 - US); G16B 5/00 (2019.02 - EP US); G16B 20/00 (2019.02 - EP US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016172485 A2 20161027; WO 2016172485 A3 20161215; AU 2016252773 A1 20171012; AU 2016252773 B2 20220602; AU 2022224860 A1 20220929; CA 2980189 A1 20161027; CN 107787332 A 20180309; CN 107787332 B 20220909; CN 116063543 A 20230505; EP 3286227 A2 20180228; HK 1250722 A1 20190111; IL 254738 A0 20171130; IL 254738 B 20210930; IL 285366 A 20210930; JP 2018516546 A 20180628; JP 2020184996 A 20201119; JP 2023002538 A 20230110; JP 6952605 B2 20211020; JP 7228545 B2 20230224; KR 102668727 B1 20240528; KR 20170140331 A 20171220; MX 2017013482 A 20180301; MX 2023003125 A 20230323; US 11116840 B2 20210914; US 2018177873 A1 20180628; US 2022409725 A1 20221229
DOCDB simple family (application)
US 2016028850 W 20160422; AU 2016252773 A 20160422; AU 2022224860 A 20220902; CA 2980189 A 20160422; CN 201680037013 A 20160422; CN 202211044002 A 20160422; EP 16720641 A 20160422; HK 18109985 A 20180802; IL 25473817 A 20170927; IL 28536621 A 20210804; JP 2017555244 A 20160422; JP 2020112362 A 20200630; JP 2022152359 A 20220926; KR 20177034034 A 20160422; MX 2017013482 A 20160422; MX 2023003125 A 20171019; US 201715789670 A 20171020; US 202117395400 A 20210805