EP 3297702 A4 20190116 - METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED IMPAIRMENTS
Title (en)
METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED IMPAIRMENTS
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON ALTERSASSOZIIERTEN LEIDEN
Title (fr)
MÉTHODES ET COMPOSITIONS PERMETTANT DE TRAITER DES TROUBLES ASSOCIÉS AU VIEILLISSEMENT
Publication
Application
Priority
- US 201562163222 P 20150518
- US 2016032907 W 20160517
Abstract (en)
[origin: WO2016187217A2] Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include reducing the 2-microglobulin (B2M) level in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments.
IPC 8 full level
A61M 1/36 (2006.01); A61K 31/7088 (2006.01); A61P 25/28 (2006.01); C12N 15/113 (2010.01)
CPC (source: CN EA EP IL KR US)
A61K 31/7088 (2013.01 - EA EP IL KR); A61K 35/14 (2013.01 - CN); A61K 38/00 (2013.01 - IL); A61K 39/395 (2013.01 - EA IL KR); A61K 48/00 (2013.01 - EA IL KR); A61M 1/16 (2013.01 - EA IL); A61M 1/3621 (2013.01 - EA IL US); A61P 25/00 (2018.01 - EA IL KR); A61P 25/14 (2018.01 - CN); A61P 25/16 (2018.01 - CN); A61P 25/28 (2018.01 - CN EA EP IL US); B01D 11/00 (2013.01 - EA IL); C07K 16/2833 (2013.01 - EA IL US); C12N 15/11 (2013.01 - EA IL); C12N 15/1138 (2013.01 - EA IL US); A61K 2039/505 (2013.01 - EA IL KR); A61M 2202/07 (2013.01 - EA IL US)
Citation (search report)
- [XI] WO 2011094535 A2 20110804 - UNIV LELAND STANFORD JUNIOR [US], et al
- [A] US 2002143283 A1 20021003 - BRAVERMAN ANDREW [US], et al
- [X] A NIEZGODA ET AL: "The effect of cladribine treatment on beta-2 microglobin in the cerebrospinal fluid and serum of patients with multiple sclerosis", NEUROL NEUROCHIR POL. 2000 MAR-APR;34(2, 1 March 2000 (2000-03-01), pages 281 - 287, XP055531915, Retrieved from the Internet <URL:http://www.ncbi.nlm.nih.gov/pubmed/10962721> [retrieved on 20181210]
- [A] S. GIORGETTI ET AL: "2-Microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity", NEPHROLOGY DIALYSIS TRANSPLANTATION., vol. 24, no. 4, 1 January 2009 (2009-01-01), GB, pages 1176 - 1181, XP055532705, ISSN: 0931-0509, DOI: 10.1093/ndt/gfn623
- See also references of WO 2016187217A2
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2016187217 A2 20161124; WO 2016187217 A3 20170105; AU 2016265948 A1 20180104; AU 2016265948 B2 20181206; AU 2019201337 A1 20190321; AU 2019201337 B2 20200514; AU 2019201337 B9 20200521; AU 2020210181 A1 20200813; AU 2020210181 B2 20220526; AU 2022221494 A1 20220929; CA 2984645 A1 20161124; CA 2984645 C 20230110; CN 107921188 A 20180417; CN 116687969 A 20230905; EA 035799 B1 20200812; EA 201792437 A1 20180430; EA 202091057 A2 20201230; EA 202091057 A3 20210331; EP 3297702 A2 20180328; EP 3297702 A4 20190116; EP 3892315 A1 20211013; HK 1248153 A1 20181012; IL 255319 A0 20171231; IL 255319 B 20221101; IL 255319 B2 20230301; JP 2018518530 A 20180712; JP 2021073264 A 20210513; JP 7134089 B2 20220909; JP 7323561 B2 20230808; KR 20180030965 A 20180327; NZ 738184 A 20190927
DOCDB simple family (application)
US 2016032907 W 20160517; AU 2016265948 A 20160517; AU 2019201337 A 20190226; AU 2020210181 A 20200728; AU 2022221494 A 20220825; CA 2984645 A 20160517; CN 201680028881 A 20160517; CN 202310374205 A 20160517; EA 201792437 A 20160517; EA 202091057 A 20160517; EP 16797159 A 20160517; EP 21162695 A 20160517; HK 18107779 A 20180615; IL 25531917 A 20171030; JP 2018512817 A 20160517; JP 2021013639 A 20210129; KR 20177035957 A 20160517; NZ 73818416 A 20160517