EP 3303598 A4 20190123 - TARGETED LIPID PARTICLES FOR SYSTEMIC DELIVERY OF NUCLEIC ACID MOLECULES TO LEUKOCYTES
Title (en)
TARGETED LIPID PARTICLES FOR SYSTEMIC DELIVERY OF NUCLEIC ACID MOLECULES TO LEUKOCYTES
Title (de)
GEZIELTE LIPIDPARTIKEL ZUR SYSTEMISCHEN ABGABE VON NUKLEINSÄUREMOLEKÜLEN AN LEUKOZYTEN
Title (fr)
PARTICULES LIPIDIQUES CIBLÉES POUR L'ADMINISTRATION SYSTÉMIQUE DE MOLÉCULES D'ACIDE NUCLÉIQUE VERS DES LEUCOCYTES
Publication
Application
Priority
- US 201562166146 P 20150526
- US 201562268526 P 20151217
- IL 2016050543 W 20160525
Abstract (en)
[origin: WO2016189532A1] Disclosed are targeted lipid based particles for delivery of nucleic acid molecules (such as si RNA) to leukocytes (such as T-Cells and B-cells). Further disclosed are uses of the targeted lipid based particles for treating Leukocytes-associated diseases, such as, cancer.
IPC 8 full level
C12N 15/88 (2006.01); A61K 9/51 (2006.01); A61K 31/105 (2006.01); A61K 39/395 (2006.01); A61P 35/02 (2006.01)
CPC (source: EP US)
A61K 9/0019 (2013.01 - EP US); A61K 9/513 (2013.01 - EP US); A61K 31/105 (2013.01 - US); A61K 31/7105 (2013.01 - EP US); A61K 31/713 (2013.01 - EP US); A61K 39/395 (2013.01 - US); A61K 47/6849 (2017.07 - EP US); A61K 47/6911 (2017.07 - EP US); A61K 48/0066 (2013.01 - US); A61P 35/02 (2017.12 - EP US); C07K 16/2812 (2013.01 - EP US); C07K 16/2896 (2013.01 - EP US); C12N 15/88 (2013.01 - EP US)
Citation (search report)
- [XY] WO 2009120247 A2 20091001 - UNIV OHIO STATE RES FOUND [US], et al
- [Y] WO 2013098813 A1 20130704 - QBI ENTPR LTD [IL], et al
- [Y] US 2014134260 A1 20140515 - HEYES JAMES [CA], et al
- [XY] B. YU ET AL: "Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia", BLOOD, vol. 121, no. 1, 3 January 2013 (2013-01-03), US, pages 136 - 147, XP055332211, ISSN: 0006-4971, DOI: 10.1182/blood-2012-01-407742
- See references of WO 2016189532A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2016189532 A1 20161201; EP 3303598 A1 20180411; EP 3303598 A4 20190123; US 10920246 B2 20210216; US 2018142261 A1 20180524; US 2021108228 A1 20210415
DOCDB simple family (application)
IL 2016050543 W 20160525; EP 16799476 A 20160525; US 201615571535 A 20160525; US 202017128736 A 20201221