EP 3307249 A1 20180418 - PHARMACEUTICAL COMPOSITION COMPRISING IVABRADINE HYDROCHLORIDE AND METHOD FOR PREPARATION THEREOF
Title (en)
PHARMACEUTICAL COMPOSITION COMPRISING IVABRADINE HYDROCHLORIDE AND METHOD FOR PREPARATION THEREOF
Title (de)
PHARMAZEUTISCHE ZUSAMMENSETZUNG MIT IVABRADIN-HYDROCHLORID UND VERFAHREN ZUR HERSTELLUNG DAVON
Title (fr)
COMPOSITION PHARMACEUTIQUE COMPRENANT DU CHLORHYDRATE D'IVABRADINE ET PROCÉDÉ POUR LA PRÉPARER
Publication
Application
Priority
- GR 20150100270 A 20150611
- EP 2016000928 W 20160606
Abstract (en)
[origin: WO2016198154A1] The present invention relates to a stable pharmaceutical formulation of solid dosage forms for oral administration containing a therapeutically effective amount of Ivabradine HCl polymorph IV or δ in combination with moisture protective excipients and/or low or non- hygroscopic anhydrous excipients in order to avoid polymorphic transformation of the active ingredient. It also relates to a process for the preparation thereof.
IPC 8 full level
A61K 9/20 (2006.01); A61K 31/55 (2006.01)
CPC (source: EP GR)
A61K 9/2009 (2013.01 - EP GR); A61K 9/2018 (2013.01 - EP); A61K 9/2031 (2013.01 - EP); A61K 9/2036 (2013.01 - EP); A61K 9/2059 (2013.01 - EP); A61K 9/28 (2013.01 - GR); A61K 31/55 (2013.01 - EP GR); A61K 47/02 (2013.01 - GR); A61P 9/10 (2017.12 - EP)
Citation (search report)
See references of WO 2016198154A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016198154 A1 20161215; EP 3307249 A1 20180418; GR 1008821 B 20160801
DOCDB simple family (application)
EP 2016000928 W 20160606; EP 16733287 A 20160606; GR 20150100270 A 20150611