Global Patent Index - EP 3307305 A4

EP 3307305 A4 20190522 - TARGETED ADAPTIVE VACCINES

Title (en)

TARGETED ADAPTIVE VACCINES

Title (de)

GERICHTETE ADAPTIVE IMPFSTOFFE

Title (fr)

VACCINS ADAPTATIFS CIBLÉS

Publication

EP 3307305 A4 20190522 (EN)

Application

EP 16808481 A 20160610

Priority

  • US 201562173783 P 20150610
  • US 2016037095 W 20160610

Abstract (en)

[origin: WO2016201377A1] The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules encoding targeted adaptive vaccines (TAVs), such as PCSK9 TAVs, TNF alpha TAVs, IL-17A TAVs, or GDF8 TAVs.

IPC 8 full level

A61K 39/00 (2006.01); A61P 3/06 (2006.01); C07K 14/31 (2006.01); C12N 9/52 (2006.01); G01N 33/569 (2006.01)

CPC (source: EP)

A61K 39/0008 (2013.01); A61P 3/06 (2017.12); C07K 14/31 (2013.01); C12N 9/52 (2013.01); C12N 9/6424 (2013.01); A61K 2039/53 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55544 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/6031 (2013.01); C07K 2319/40 (2013.01)

Citation (search report)

  • [Y] US 2014206852 A1 20140724 - HOGE STEPHEN G [US], et al
  • [YP] WO 2015085318 A2 20150611 - MODERNA THERAPEUTICS INC [US]
  • [A] WO 2015024666 A1 20150226 - CUREVAC GMBH [DE]
  • [Y] GERGANA GALABOVA ET AL: "Peptide-Based Anti-PCSK9 Vaccines - An Approach for Long-Term LDLc Management", PLOS ONE, vol. 9, no. 12, 4 December 2014 (2014-12-04), pages e114469, XP055579730, DOI: 10.1371/journal.pone.0114469
  • [Y] PATRICK MIDOUX ET AL: "Lipid-based mRNA vaccine delivery systems", EXPERT REVIEW OF VACCINES, vol. 14, no. 2, 12 February 2015 (2015-02-12), GB, pages 221 - 234, XP055439935, ISSN: 1476-0584, DOI: 10.1586/14760584.2015.986104
  • [Y] S. HOLTKAMP ET AL: "Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells", BLOOD, vol. 108, no. 13, 15 December 2006 (2006-12-15), pages 4009 - 4017, XP055044965, ISSN: 0006-4971, DOI: 10.1182/blood-2006-04-015024
  • [Y] TOMPKINS STEPHEN MARK ET AL: "Matrix protein 2 vaccination and protection against influenza viruses, including subtype H5N1", EMERGING INFECTIOUS DISE, EID, ATLANTA, GA, US, vol. 13, no. 3, 1 March 2007 (2007-03-01), pages 426 - 435, XP009089369, ISSN: 1080-6040
  • [T] NORBERT PARDI ET AL: "mRNA vaccines - a new era in vaccinology", NATURE REVIEWS. DRUG DISCOVERY, vol. 17, no. 4, 12 January 2018 (2018-01-12), GB, pages 261 - 279, XP055524319, ISSN: 1474-1776, DOI: 10.1038/nrd.2017.243
  • See references of WO 2016201377A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2016201377 A1 20161215; EP 3307305 A1 20180418; EP 3307305 A4 20190522

DOCDB simple family (application)

US 2016037095 W 20160610; EP 16808481 A 20160610