Global Patent Index - EP 3310342 A4

EP 3310342 A4 20190306 - INORGANIC CONTROLLED RELEASE PARTICLES WITH FAST DRUG LOADING

Title (en)

INORGANIC CONTROLLED RELEASE PARTICLES WITH FAST DRUG LOADING

Title (de)

ANORGANISCHE RETARD-PARTIKEL MIT SCHNELLER WIRKSTOFFBELADUNG

Title (fr)

PARTICULES INORGANIQUES À LIBÉRATION PROLONGÉE À CHARGE RAPIDE EN SUBSTANCE MÉDICAMENTEUSE

Publication

EP 3310342 A4 20190306 (EN)

Application

EP 16812105 A 20160513

Priority

  • US 201562180345 P 20150616
  • US 2016032408 W 20160513

Abstract (en)

[origin: WO2016204896A1] Disclosed herein are nanoparticles comprising an inorganic material having pores that can quickly absorb pharmaceutical moieties and then release such moieites in a controlled fashion for an extended period of time. The nanoparticles can be aggregated in order to form microaggregates that provide the same advantages of quick absorption and controlled release of pharmaceutical moieties. Quick absorption permits the preparation of drug-loaded nanoparticles and microaggregates essentially contemporaneously with the time of treatment, such as during a surgical process. Methods of preparing such nanoparticles and microaggregates are also provided, as are methods for administering a pharmaceutical moiety using the nanoparticles and microaggregates.

IPC 8 full level

A61K 47/69 (2017.01); A61K 9/14 (2006.01); A61K 9/50 (2006.01); A61P 31/04 (2006.01)

CPC (source: EP)

A61K 9/0019 (2013.01); A61K 9/5115 (2013.01); A61K 47/6923 (2017.07); A61P 31/04 (2017.12)

Citation (search report)

  • [XY] EP 1741717 A1 20070110 - IMEC INTER UNI MICRO ELECTR [BE]
  • [Y] EP 2259798 B1 20131211 - BAXTER INT [US], et al
  • [Y] US 2004076681 A1 20040422 - DENNIS DONN M [US], et al
  • [Y] WO 2012149268 A1 20121101 - SELECTA BIOCIENCES INC [US], et al
  • [XYI] XUANJUN WU ET AL: "Cytosolic delivery of proteins mediated by aldehyde-displaying silica nanoparticles with pH-responsive characteristics", JOURNAL OF MATERIALS CHEMISTRY, vol. 22, no. 33, 2012, pages 17121, XP055543145, ISSN: 0959-9428, DOI: 10.1039/c2jm33434h
  • [XY] YANG LING ET AL: "One-pot synthesis of aldehyde-functionalized mesoporous silica-Fe3O4nanocomposites for immobilization of penicillin G acylase", MICROPOROUS AND MESOPOROUS MATERIALS, vol. 197, 5 June 2014 (2014-06-05), pages 1 - 7, XP029015821, ISSN: 1387-1811, DOI: 10.1016/J.MICROMESO.2014.05.044
  • [Y] GAO ZHENYUAN ET AL: "Aldehydepropyl-functionalized mesostructured cellular foams: Efficient supports for immobilization of penicillin G acylase", JOURNAL OF MOLECULAR CATALYSIS. B, ENZYMATIC, vol. 105, 21 April 2014 (2014-04-21), pages 111 - 117, XP029026137, ISSN: 1381-1177, DOI: 10.1016/J.MOLCATB.2014.04.006
  • [Y] BR]NING C ET AL: "Aldehyde-functionalized ethoxysilanes as new enzyme immobilization reagents", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS, 1995, pages 2323 - 2324, XP002965494, ISSN: 0022-4936, DOI: 10.1039/C39950002323
  • [Y] LATTERICH MARTIN ET AL: "Label-free detection of biomolecular interactions in real time with a nano-porous silicon-based detection method", PROTEOME SCIENCE, vol. 6, no. 1, 4 November 2008 (2008-11-04), pages 31, XP021043843, ISSN: 1477-5956, DOI: 10.1186/1477-5956-6-31
  • See references of WO 2016204896A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2016204896 A1 20161222; CA 2989795 A1 20161222; CA 2989795 C 20231212; EP 3310342 A1 20180425; EP 3310342 A4 20190306

DOCDB simple family (application)

US 2016032408 W 20160513; CA 2989795 A 20160513; EP 16812105 A 20160513