EP 3310440 A1 20180425 - ANTIBODY DRUG CONJUGATES (ADCS) AND ANTIBODY PRODRUG CONJUGATES (APDCS) WITH ENZYMATICALLY CLEAVABLE GROUPS
Title (en)
ANTIBODY DRUG CONJUGATES (ADCS) AND ANTIBODY PRODRUG CONJUGATES (APDCS) WITH ENZYMATICALLY CLEAVABLE GROUPS
Title (de)
BINDER-WIRKSTOFF-KONJUGATE (ADCS) UND BINDER-PRODRUG-KONJUGATE (APDCS) MIT ENZYMATISCH SPALTBAREN GRUPPEN
Title (fr)
CONJUGUÉS ANTICORPS-MÉDICAMENT (ADC) ET CONJUGUÉS LIEUR-PROMÉDICAMENT (APDC) À GROUPES ENZYMATIQUEMENT CLIVABLES
Publication
Application
Priority
- EP 15173102 A 20150622
- EP 16160738 A 20160316
- EP 2016064118 W 20160620
Abstract (en)
[origin: WO2016207089A1] The invention relates to novel antibody prodrug conjugates (ADCs) in which antibodies with inactive precursor compounds of kinesin spindel protein-inhibitors are conjugated, and to antibody drug conjugate (ADCs) and to a method for producing said APDCs or ADCs.
IPC 8 full level
A61P 35/00 (2006.01)
CPC (source: CN EP IL KR RU US)
A61K 31/4025 (2013.01 - CN EP IL US); A61K 31/4439 (2013.01 - CN EP IL US); A61K 47/65 (2017.08 - CN IL US); A61K 47/68 (2017.08 - CN RU); A61K 47/6803 (2017.08 - CN EP IL KR US); A61K 47/6849 (2017.08 - CN EP IL KR US); A61K 47/6851 (2017.08 - CN IL US); A61K 47/6855 (2017.08 - CN EP IL KR US); A61K 47/6857 (2017.08 - CN EP IL KR US); A61K 47/6863 (2017.08 - CN EP IL KR US); A61K 47/6865 (2017.08 - CN EP IL KR US); A61P 35/00 (2018.01 - CN EP IL RU); A61P 43/00 (2018.01 - CN EP IL); C07D 207/335 (2013.01 - RU); A61K 2300/00 (2013.01 - IL US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016207089 A1 20161229; AU 2016282723 A1 20180118; AU 2016282723 B2 20210923; AU 2021290341 A1 20220203; BR 112017027813 A2 20180828; CA 2990076 A1 20161229; CN 108025084 A 20180511; CN 114917361 A 20220819; EP 3310440 A1 20180425; IL 256394 A 20180430; IL 256394 B 20220401; IL 291160 A 20220501; JP 2018524321 A 20180830; JP 2022025122 A 20220209; JP 6971858 B2 20211124; JP 7394103 B2 20231207; KR 20180018808 A 20180221; MX 2017017172 A 20180223; PE 20180610 A1 20180409; RU 2018102153 A 20190725; RU 2018102153 A3 20191203; RU 2751512 C2 20210714; SG 10201908685Q A 20191030; SG 11201710639Y A 20180130; TW 201703798 A 20170201; TW 202216213 A 20220501; TW I735448 B 20210811; US 11123439 B2 20210921; US 2018169256 A1 20180621; US 2023039341 A1 20230209; ZA 201800395 B 20210728
DOCDB simple family (application)
EP 2016064118 W 20160620; AU 2016282723 A 20160620; AU 2021290341 A 20211223; BR 112017027813 A 20160620; CA 2990076 A 20160620; CN 201680048607 A 20160620; CN 202210272790 A 20160620; EP 16730833 A 20160620; IL 25639417 A 20171218; IL 29116022 A 20220307; JP 2017566068 A 20160620; JP 2021179717 A 20211102; KR 20187001793 A 20160620; MX 2017017172 A 20160620; PE 2017002810 A 20160620; RU 2018102153 A 20160620; SG 10201908685Q A 20160620; SG 11201710639Y A 20160620; TW 105119613 A 20160622; TW 110126294 A 20160622; US 201615739111 A 20160620; US 202117374756 A 20210713; ZA 201800395 A 20180119