Title (en)

ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-B7H3-ANTIBODIES

Title (de)

ANTIKÖRPER-WIRKSTOFF-KONJUGATE (ADCS) VON KSP-INHIBITOREN MIT ANTI-B7H3-ANTIKÖRPERN

Title (fr)

CONJUGUÉS ANTICORPS-PRINCIPE ACTIF (ADC) D'INHIBITEURS DE KSP AVEC DES ANTICORPS ANTI-B7H3

Publication

EP 3313522 A1 20180502 (DE)

Application

EP 16733024 A 20160620

Priority

• EP 15173485 A 20150623
• EP 2016064158 W 20160620

Abstract (en)

[origin: WO2016207104A1] The invention relates to novel antibody drug conjugates (ADCs), active metabolites of said ADCs, to methods for producing said ADCs, to the use of said ADCs for the treatment and/or prevention of diseases, and to the use of said ADCs for the production of medicaments for the treatment and/or prevention of diseases, in particular hyperproliferative and angiogenic diseases, such as cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.

IPC 8 full level

A61P 35/00 (2006.01)

CPC (source: EP US)

A61K 31/40 (2013.01 - US); A61K 47/6803 (2017.08 - EP US); A61K 47/6849 (2017.08 - EP US); A61K 47/6855 (2017.08 - EP); A61K 47/6857 (2017.08 - EP); A61K 47/6863 (2017.08 - EP); A61K 47/6865 (2017.08 - EP US); A61P 9/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2016207104 A1 20161229; CA 2990411 A1 20161229; CN 108025086 A 20180511; EP 3313522 A1 20180502; JP 2018524314 A 20180830; JP 6905941 B2 20210721; TW 201718020 A 20170601; US 11071788 B2 20210727; US 2020138970 A1 20200507

DOCDB simple family (application)

EP 2016064158 W 20160620; CA 2990411 A 20160620; CN 201680049039 A 20160620; EP 16733024 A 20160620; JP 2017565712 A 20160620; TW 105119615 A 20160622; US 201615739471 A 20160620