EP 3313524 A1 20180502 - ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-CD123-ANTIBODIES
Title (en)
ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-CD123-ANTIBODIES
Title (de)
ANTIKÖRPER-WIRKSTOFF-KONJUGATE (ADCS) VON KSP-INHIBITOREN MIT ANTI-CD123-ANTIKÖRPERN
Title (fr)
CONJUGUÉS ANTICORPS-PRINCIPE ACTIF (ADC) D'INHIBITEURS DE KSP AVEC DES ANTICORPS ANTI-CD123
Publication
Application
Priority
- EP 15173479 A 20150623
- EP 2016064133 W 20160620
Abstract (en)
[origin: WO2016207098A1] The invention relates to novel antibody drug conjugates (ADCs), active metabolites of said ADCs, to methods for producing said ADCs, to the use of said ADCs for the treatment and/or prevention of diseases, and to the use of said ADCs for the production of medicaments for the treatment and/or prevention of diseases, in particular hyperproliferative and angiogenic diseases, such as cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.
IPC 8 full level
A61P 35/00 (2006.01)
CPC (source: EP US)
A61K 31/40 (2013.01 - EP US); A61K 31/4025 (2013.01 - EP US); A61K 47/6803 (2017.08 - EP US); A61K 47/6849 (2017.08 - EP US); A61K 47/6851 (2017.08 - EP US); A61P 35/00 (2018.01 - EP US); C07D 207/33 (2013.01 - US); C07K 16/2866 (2013.01 - US); A61K 2039/505 (2013.01 - US); A61K 2039/572 (2013.01 - US); C07K 2317/24 (2013.01 - US); C07K 2317/56 (2013.01 - US); C07K 2317/565 (2013.01 - US); C07K 2317/73 (2013.01 - US); C07K 2317/76 (2013.01 - US); C07K 2317/92 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2016207098 A1 20161229; AR 108156 A1 20180725; CA 2990398 A1 20161229; CN 107921146 A 20180417; EP 3313524 A1 20180502; JP 2018520130 A 20180726; JP 6768011 B2 20201014; TW 201720463 A 20170616; US 10744205 B2 20200818; US 2018318437 A1 20181108
DOCDB simple family (application)
EP 2016064133 W 20160620; AR P160101871 A 20160622; CA 2990398 A 20160620; CN 201680048978 A 20160620; EP 16736011 A 20160620; JP 2017565697 A 20160620; TW 105119594 A 20160622; US 201615739134 A 20160620