Global Patent Index - EP 3322823 A4

EP 3322823 A4 20190619 - METHODS FOR DIAGNOSIS, PROGNOSIS AND MONITORING OF BREAST CANCER AND REAGENTS THEREFOR

Title (en)

METHODS FOR DIAGNOSIS, PROGNOSIS AND MONITORING OF BREAST CANCER AND REAGENTS THEREFOR

Title (de)

VERFAHREN ZUR DIAGNOSE, PROGNOSE UND ÜBERWACHUNG VON BRUSTKREBS UND REAGENZIEN DAFÜR

Title (fr)

PROCÉDÉ DE DIAGNOSTIC, DE PRONOSTIC ET DE SUIVI D'UN CANCER DU SEIN ET RÉACTIFS CORRESPONDANTS

Publication

EP 3322823 A4 20190619 (EN)

Application

EP 16823558 A 20160714

Priority

  • US 201562192540 P 20150714
  • AU 2016050615 W 20160714

Abstract (en)

[origin: WO2017008117A1] The present disclosure generally relates to methods and reagents for the diagnosis, prognosis or the monitoring of estrogen receptor 1 (ESR1) positive breast cancer, for example, ESR1 positive breast cancer which is responsive to endocrine therapy and/or ESR1 positive breast cancer which is refractory to endocrine therapy. The present disclosure also relates generally to treatment management of ESR1 positive breast cancer.

IPC 8 full level

C12Q 1/68 (2018.01); C12Q 1/48 (2006.01); G01N 33/574 (2006.01)

CPC (source: EP)

C12Q 1/68 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/154 (2013.01)

Citation (search report)

  • [A] WO 03000189 A2 20030103 - BAYLOR COLLEGE MEDICINE [US], et al
  • [A] WO 2006004597 A2 20060112 - UNIV SOUTHERN CALIFORNIA [US], et al
  • [A] CAROLYN L SMITH ET AL: "Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence", BREAST CANCER RESEARCH AND TREATMENT, KLUWER ACADEMIC PUBLISHERS, BO, vol. 136, no. 1, 27 September 2012 (2012-09-27), pages 253 - 265, XP035125727, ISSN: 1573-7217, DOI: 10.1007/S10549-012-2262-7
  • [A] RYO AKIHIDE ET AL: "Pinning down HER2-ER crosstalk in SMRT regulation.", TRENDS IN BIOCHEMICAL SCIENCES APR 2009, vol. 34, no. 4, April 2009 (2009-04-01), pages 162 - 165, XP002791216, ISSN: 0968-0004
  • [A] T VAN AGTHOVEN ET AL: "CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer", BRITISH JOURNAL OF CANCER, vol. 101, no. 11, 10 November 2009 (2009-11-10), GB, pages 1824 - 1832, XP055587459, ISSN: 0007-0920, DOI: 10.1038/sj.bjc.6605423
  • [A] K W MERRELL ET AL: "Differential recruitment of nuclear receptor coregulators in ligand-dependent transcriptional repression by estrogen receptor-[alpha]", ONCOGENE, vol. 30, no. 13, 22 November 2010 (2010-11-22), London, pages 1608 - 1614, XP055587477, ISSN: 0950-9232, DOI: 10.1038/onc.2010.528
  • [A] L. ZHANG ET AL: "SpliceArray Profiling of Breast Cancer Reveals a Novel Variant of NCOR2/SMRT That Is Associated with Tamoxifen Resistance and Control of ER? Transcriptional Activity", CANCER RESEARCH, vol. 73, no. 1, 1 November 2012 (2012-11-01), Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA, pages 246 - 255, XP055367636, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-12-2241
  • See references of WO 2017008117A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2017008117 A1 20170119; AU 2016293381 A1 20180125; CN 107922977 A 20180417; EP 3322823 A1 20180523; EP 3322823 A4 20190619

DOCDB simple family (application)

AU 2016050615 W 20160714; AU 2016293381 A 20160714; CN 201680051447 A 20160714; EP 16823558 A 20160714