EP 3332014 A4 20190123 - METHOD FOR PRODUCING AN ANIMAL COMPRISING A GERMLINE GENETIC MODIFICATION
Title (en)
METHOD FOR PRODUCING AN ANIMAL COMPRISING A GERMLINE GENETIC MODIFICATION
Title (de)
VERFAHREN ZUR HERSTELLUNG EINES TIERES MIT EINER GENETISCHEN KEIMBAHNMODIFIKATION
Title (fr)
PROCÉDÉ DE PRODUCTION D'UN ANIMAL COMPRENANT UNE MODIFICATION GÉNÉTIQUE DES CELLULES GERMINALES
Publication
Application
Priority
- AU 2015903164 A 20150807
- AU 2016050714 W 20160805
Abstract (en)
[origin: WO2017024343A1] The present invention relates to methods for producing a non-human animal, such as an avian, comprising a targeted germline genetic modification wherein a nuclease, which may be CRISPR, ZFN or TALEN, is delivered to spermatozoa prior to oocyte fertilization.
IPC 8 full level
C12N 15/90 (2006.01); A01K 67/027 (2006.01); C12N 15/88 (2006.01)
CPC (source: EP US)
A01K 67/0275 (2013.01 - EP US); C12N 9/22 (2013.01 - EP US); C12N 15/88 (2013.01 - US); C12N 15/90 (2013.01 - EP US); A01K 2217/072 (2013.01 - EP US); A01K 2227/30 (2013.01 - EP US); A01K 2267/02 (2013.01 - EP US); C07H 21/02 (2013.01 - US); C12N 2310/20 (2017.04 - US)
Citation (search report)
- [X] T. S. PARK ET AL: "Targeted gene knockout in chickens mediated by TALENs", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 111, no. 35, 19 August 2014 (2014-08-19), US, pages 12716 - 12721, XP055248659, ISSN: 0027-8424, DOI: 10.1073/pnas.1410555111
- [XP] COOPER C A ET AL: "Developing knockout chickens in one generation via sperm transfection with PGE tools", TRANSGENIC RESEARCH, vol. 25, no. 1, February 2016 (2016-02-01), & UC-DAVIS TRANSGENIC ANIMAL RESEARCH CONFERENCE X (TARC X); TAHOE, CA, USA; AUGUST 09 -12, 2015, pages 119, XP002786615
- [AP] ISAO OISHI ET AL: "Targeted mutagenesis in chicken using CRISPR/Cas9 system", SCIENTIFIC REPORTS, vol. 6, 1 January 2016 (2016-01-01), pages 23980, XP055365536, DOI: 10.1038/srep23980
- [AP] LAZAR DIMITROV ET AL: "Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells", PLOS ONE, vol. 11, no. 4, 21 April 2016 (2016-04-21), pages e0154303, XP055523968, DOI: 10.1371/journal.pone.0154303
- [AP] NADÈGE VÉRON ET AL: "CRISPR mediated somatic cell genome engineering in the chicken", DEVELOPMENTAL BIOLOGY, vol. 407, no. 1, 1 November 2015 (2015-11-01), AMSTERDAM, NL, pages 68 - 74, XP055523970, ISSN: 0012-1606, DOI: 10.1016/j.ydbio.2015.08.007
- [T] COOPER CAITLIN A ET AL: "Generation of gene edited birds in one generation using sperm transfection assisted gene editing (STAGE)", TRANSGENIC RESEARCH, SPRINGER NETHERLANDS, NL, vol. 26, no. 3, 28 November 2016 (2016-11-28), pages 331 - 347, XP036230703, ISSN: 0962-8819, [retrieved on 20161128], DOI: 10.1007/S11248-016-0003-0
- See references of WO 2017024343A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2017024343 A1 20170216; AU 2016305490 A1 20180301; AU 2016305490 B2 20220714; AU 2022252811 A1 20230105; BR 112018002558 A2 20180925; CN 108474007 A 20180831; EP 3332014 A1 20180613; EP 3332014 A4 20190123; US 11606940 B2 20230321; US 2019014757 A1 20190117; US 2023232793 A1 20230727
DOCDB simple family (application)
AU 2016050714 W 20160805; AU 2016305490 A 20160805; AU 2022252811 A 20221014; BR 112018002558 A 20160805; CN 201680057903 A 20160805; EP 16834309 A 20160805; US 201615750605 A 20160805; US 202318166368 A 20230208